Evidence map›Paper›PMID 38618460›Full record

ArticleCureus2024

A Sodium Oxychlorosene-Based Infection Prevention Protocol Safely Decreases Postoperative Wound Infections in Adult Spinal Deformity Surgery.

Vincent J Alentado, Fezaan A Kazi, Caroline A Potts, Mohamed A Zaazoue, Eric A Potts, Saad A Khairi

Open access · diamondAbstract read
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Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vincent J AlentadoNeurological Surgery, Goodman Campbell Brain and Spine, Ascension St. Vincent Hospital Indianapolis, Indianapolis, USA.
Fezaan A KaziMedicine, Indiana University School of Medicine, Indianapolis, USA.
Caroline A PottsNeurological Surgery, Goodman Campbell Brain and Spine, Ascension St. Vincent Hospital Indianapolis, Indianapolis, USA.
Mohamed A ZaazoueNeurological Surgery, Indiana University School of Medicine, Indianapolis, USA.
Eric A PottsNeurological Surgery, Goodman Campbell Brain and Spine, Ascension St. Vincent Hospital Indianapolis, Indianapolis, USA.
Saad A KhairiNeurological Surgery, Goodman Campbell Brain and Spine, Ascension St. Vincent Hospital Indianapolis, Indianapolis, USA.
St. Vincent Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study sought to determine the efficacy of a complex multi-institutional sodium oxychlorosene-based infection protocol for decreasing the rate of surgical site infection after instrumented spinal surgery for adult spinal deformity (ASD). Infection prevention protocols have not been previously studied in ASD patients.

methodsA retrospective analysis was performed of patients who underwent posterior instrumented spinal fusion of the thoracic or lumbar spine for deformity correction between January 1, 2011, and May 31, 2019. The efficacy of a multi-modal infection prevention protocol was examined. The infection prevention bundle consisted of methicillin-resistant

resultsAbout 254 patients fit the inclusion criteria. Among these patients, nine (3.5%) experienced post-surgical deep-wound infection. Demographics and surgical characteristics amongst infected and non-infected cohorts were similar, although diabetes trended towards being more prevalent in patients who developed a postoperative wound infection (p=0.07). Among 222 patients (87.4%) who achieved a minimum of two years of follow-ups, 184 patients (82.9%) experienced successful fusion, comparing favorably with pseudarthrosis rates in the ASD literature. Rates of pseudarthrosis and proximal junction kyphosis were similar amongst infected and non-infected patients.

conclusionAn intraoperative comprehensive sodium oxychlorosene-based infection prevention protocol helped to provide a low rate of infection after major deformity correction without negatively impacting other postoperative procedure-related metrics.

Indexed as

complicationsinfection prevention protocoloxychlorosenespinal deformity surgeryspine surgery

Identifiers

PMID38618460
PMCPMC11009892
OpenAlexW4392743387

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.