Evidence map›Paper›PMID 38618244›Full record

ArticleJournal of pharmaceutical analysis2024

The "depict" strategy for discovering new compounds in complex matrices: Lycibarbarspermidines as a case.

Chen Han, Zhixin Zhang, Zhiyang Feng, Chuanjia Zhai, Xuejiao Li, Yulian Shi, Xiang Li, Miao Li, Ying Wang, Gan Luo and 1 more

Abstract read
In one paragraph

Article in Journal of pharmaceutical analysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Goat's Milk Powder Enriched with Red (Foods (Basel, Switzerland) · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chen HanDepartment of Chinese Medicine Analysis, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Zhixin ZhangDepartment of Chinese Medicine Analysis, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Zhiyang FengDepartment of Chinese Medicine Analysis, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Chuanjia ZhaiDepartment of Chinese Medicine Analysis, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Xuejiao LiDepartment of Chinese Medicine Analysis, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Yulian ShiDepartment of Chinese Medicine Analysis, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Xiang LiDepartment of Chinese Medicine Analysis, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Miao LiDepartment of Chinese Medicine Analysis, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Ying WangDepartment of Chinese Medicine Analysis, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Gan LuoDepartment of Chinese Medicine Analysis, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Xiaoyan GaoDepartment of Chinese Medicine Analysis, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The comprehensive detection and identification of active ingredients in complex matrices is a crucial challenge. Liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) is the most prominent analytical platform for the exploration of novel active compounds from complex matrices. However, the LC-HRMS-based analysis workflow suffers from several bottleneck issues, such as trace content of target compounds, limited acquisition for fragment information, and uncertainty in interpreting relevant MS

Indexed as

Complex matricesMass spectrometric detectionNovel lycibarbarspermidinesWeak response signals

Identifiers

PMID38618244
PMCPMC11010613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.