Evidence map›Paper›PMID 38618055›Full record

ArticleJournal of dental sciences2024

3D-bioprinted alginate-based bioink scaffolds with β-tricalcium phosphate for bone regeneration applications.

Yi-Fan Wu, Ya-Ting Wen, Eisner Salamanca, Lwin Moe Aung, Yan-Qiao Chao, Chih-Yun Chen, Ying-Sui Sun, Wei-Jen Chang

Open access · goldAbstract read
In one paragraph

Article in Journal of dental sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yi-Fan WuSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Ya-Ting WenDepartment of Medical Education, Taichung Veterans General Hospital, Taichung, Taiwan.
Eisner SalamancaSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Lwin Moe AungSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Yan-Qiao ChaoSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Chih-Yun ChenSchool of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Ying-Sui SunSchool of Dental Technology, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Wei-Jen ChangSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Taipei Medical University · TWMing Chuan University · TWTaichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: 3D-printed bone tissue engineering is becoming recognized as a key approach in dentistry for creating customized bone regeneration treatments fitting patients bone defects requirements. 3D bioprinting offers an innovative method to fabricate detailed 3D structures, closely emulating the native bone micro-environment and better bone regeneration. This study aimed to develop an 3D-bioprintable scaffold using a combination of alginate and β-tricalcium phosphate (β-TCP) with the Cellink® BioX printer, aiming to advance the field of tissue engineering. Materials and methods: The physical and biological properties of the resulting 3D-printed scaffolds were evaluated at 10 %, 12 %, and 15 % alginate combined with 10 % β-TCP. The scaffolds were characterized through printability, swelling behavior, degradability, and element analysis. The biological assessment included cell viability, alkaline phosphatase (ALP) activity. Results: 10 % alginate/β-TCP 3D printed at 25 °C scaffold demonstrated the optimal condition for printability, swelling capability, and degradability of cell growth and nutrient diffusion. Addition of β-TCP particles significantly improved the 3D printed material viscosity over only alginate ( Conclusion: This study demonstrated

Indexed as

AlginateBeta-tricalcium phosphate (β-TCP)BioprintingBone regeneration

Identifiers

PMID38618055
PMCPMC11010696
OpenAlexW4390820293

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.