Evidence map›Paper›PMID 38618031›Full record

ArticleJournal of animal science and technology2024

Constipation anti-aging effects by dairy-based lactic acid bacteria.

Mohamad Hafis Jaafar, Pei Xu, Uma-Mageswary Mageswaran, Shandra-Devi Balasubramaniam, Maheswaran Solayappan, Jia-Jie Woon, Cindy Shuan-Ju Teh, Svetoslav Dimitrov Todorov, Yong-Ha Park, Guoxia Liu and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of animal science and technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Protective Effects ofJournal of microbiology and biotechnology · 2026
    Article
  2. Article
  3. Enhanced Longevity and Immunity inFood science of animal resources · 2025
    Article
  4. Metabolic Regulation of Longevity and Immune Response inJournal of microbiology and biotechnology · 2024
    Article
  5. Fermenting Acerola (Foods (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Mohamad Hafis JaafarBioprocess Technology, School of Industrial Technology, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID https://orcid.org/0000-0001-8219-0677
Pei XuBioprocess Technology, School of Industrial Technology, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID https://orcid.org/0009-0005-0841-6152
Uma-Mageswary MageswaranBioprocess Technology, School of Industrial Technology, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID https://orcid.org/0009-0005-7941-6635
Shandra-Devi BalasubramaniamFaculty of Medicine, AIMST University, Bedong 08100, Kedah, Malaysia.ORCID https://orcid.org/0000-0002-3217-9514
Maheswaran SolayappanFaculty of Applied Sciences, AIMST University, Bedong 08100, Kedah, Malaysia.ORCID https://orcid.org/0000-0002-2629-4583
Jia-Jie WoonDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.ORCID https://orcid.org/0000-0003-4074-8040
Cindy Shuan-Ju TehDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.ORCID https://orcid.org/0000-0002-9062-3839
Svetoslav Dimitrov TodorovProBacLab, Department of Food Science and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo 05508-090, Brazil.ORCID https://orcid.org/0000-0002-6377-3305
Yong-Ha ParkProbionic Corp., Iksan 54576, Korea.ORCID https://orcid.org/0000-0002-8795-9075
Guoxia LiuCAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100864, China.ORCID https://orcid.org/0000-0001-7924-0733
Min-Tze LiongBioprocess Technology, School of Industrial Technology, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID https://orcid.org/0000-0002-4471-8271
Universiti Sains Malaysia · MYAIMST University · MYUniversity Malaya Medical Centre · MYChinese Academy of Sciences · CNUniversidade de São Paulo · BRWonkwang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Constipation, which refers to difficulties in defecation and infrequent bowel movement in emptying the gastrointestinal system that ultimately produces hardened fecal matters, is a health concern in livestock and aging animals. The present study aimed to evaluate the potential effects of dairy-isolated lactic acid bacteria (LAB) strains to alleviate constipation as an alternative therapeutic intervention for constipation treatment in the aging model. Rats were aged via daily subcutaneous injection of D-galactose (600 mg/body weight [kg]), prior to induction of constipation via oral administration of loperamide hydrochloride (5 mg/body weight [kg]). LAB strains (

Indexed as

AgingConstipationDairy-based lactic acid bacteria (LAB)Dairy foodsProbiotics

Identifiers

PMID38618031
PMCPMC11007456
OpenAlexW4386645206

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.