Evidence map›Paper›PMID 38617561›Full record

ArticleiScience2024

scMoresDB: A comprehensive database of single-cell multi-omics data for human respiratory system.

Kang Chen, Yutong Han, Yanni Wang, Dingli Zhou, Fanjie Wu, Wenhao Cai, Shikang Zheng, Qinyuan Xiao, Haiyue Zhang, Weizhong Li

Open access · goldAbstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kang ChenZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Yutong HanZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Yanni WangZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Dingli ZhouZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Fanjie WuZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Wenhao CaiZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Shikang ZhengZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Qinyuan XiaoZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Haiyue ZhangZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Weizhong LiZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human respiratory system is a complex and important system that can suffer a variety of diseases. Single-cell sequencing technologies, applied in many respiratory disease studies, have enhanced our ability in characterizing molecular and phenotypic features at a single-cell resolution. The exponentially increasing data from these studies have consequently led to difficulties in data sharing and analysis. Here, we present scMoresDB, a single-cell multi-omics database platform with extensive omics types tailored for human respiratory diseases. scMoresDB re-analyzes single-cell multi-omics datasets, providing a user-friendly interface with cross-omics search capabilities, interactive visualizations, and analytical tools for comprehensive data sharing and integrative analysis. Our example applications highlight the potential significance of BSG receptor in SARS-CoV-2 infection as well as the involvement of HHIP and TGFB2 in the development and progression of chronic obstructive pulmonary disease. scMoresDB significantly increases accessibility and utility of single-cell data relevant to human respiratory system and associated diseases.

Indexed as

Biological databaseBody systemData processing in systems biologyHumanTranscriptomics

Identifiers

PMID38617561
PMCPMC11015448
OpenAlexW4393198111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.