Evidence map›Paper›PMID 38617547›Full record

ArticleInternational journal of biological sciences2024

TREM2 promotes macrophage polarization from M1 to M2 and suppresses osteoarthritis through the NF-κB/CXCL3 axis.

Chao Fang, Rui Zhong, Shuai Lu, Gang Yu, Zhilin Liu, Chengyuan Yan, Jingyu Gao, Yang Tang, Yingming Wang, Qichun Zhao and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 1 pooled it
19.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.

  1. Pooled it
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  11. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
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  16. The role of DAP12 in immune-related inflammatory diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Chao FangDepartment of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China.
Rui ZhongDepartment of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China.
Shuai LuDepartment of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China.
Gang YuDepartment of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China.
Zhilin LiuDepartment of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China.
Chengyuan YanDepartment of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China.
Jingyu GaoDepartment of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China.
Yang TangDepartment of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China.
Yingming WangDepartment of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China.
Qichun ZhaoDepartment of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China.
Xinzhe FengDepartment of Joint Bone Disease Surgery, Changhai Hospital, Naval Medical University, Shanghai, 200433, China.
University of Science and Technology of China · CNSecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NF-kappa BOsteoarthritisAnimalsChemokines, CXCInflammationMembrane GlycoproteinsMicePhosphatidylinositol 3-KinasesReceptors, ImmunologicSignal TransductionChemokines, CXCCxcl3 protein, mouseMembrane GlycoproteinsNF-kappa BPhosphatidylinositol 3-KinasesReceptors, ImmunologicTrem2 protein, mouseCXCL3MacrophageNF-κBOsteoarthritisTREM2

Identifiers

PMID38617547
PMCPMC11008261
OpenAlexW4392827801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.