ReviewEye and brain2024
Detecting Abnormal Eye Movements in Patients with Neurodegenerative Diseases - Current Insights.
Review in Eye and brain, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- Article
- Pace-Induced Saccades in Essential Tremor Differ from Those in Parkinson's Disease and Degenerative Ataxias.Journal of clinical medicine · 2026Article
- How artificial intelligence is shaping neuropsychology: A focus on cognitive assessment of neurodegenerative disorders.Journal of neuropsychology · 2026Review
- Eye tracking as a digital biomarker in neurodegenerative diseases.Journal of neurology · 2026Review
- Eye Movement Classification Using Neuromorphic Vision Sensors.Journal of eye movement research · 2026Article
- Early screening of mild cognitive impairment based on eye-tracking technology: a cross-sectional study.Aging clinical and experimental research · 2026Article
- Exploring eye movement abnormalities as objective biomarkers for Parkinson's disease utilizing virtual reality-based eye tracking.BMC neurology · 2026Article
- EYE movement abnormalities in Parkinson's disease: optometric screening and rehabilitation.Clinical parkinsonism & related disorders · 2026Review
- Article
- Visual Function in Alzheimer's Disease: Current Understanding and Potential Mechanisms Behind Visual Impairment.Journal of clinical medicine · 2025Review
- A digital measure of eye movements during reading sensitively captures oculomotor and speech dysfunction, early changes, and disease progression in ataxias.medRxiv : the preprint server for health sciences · 2025Article
- Validation of reading as a predictor of mild cognitive impairment.Scientific reports · 2025Article
- Multimodal Digital Phenotyping of Behavior in a Neurology Clinic: Development of the Neurobooth Platform and the First Two Years of Data Collection.medRxiv : the preprint server for health sciences · 2025Article
- Motor symptoms of Parkinson's disease: critical markers for early AI-assisted diagnosis.Frontiers in aging neuroscience · 2025Review
- Progress in the Study of Diagnostic Methods for Central Acute Vestibular Syndrome of a Vascular Cause.International journal of general medicine · 2025Review
- Abnormal eye movements: relationship with clinical symptoms and predictive value for Alzheimer's disease.Frontiers in aging neuroscience · 2024Article
- 3DeepVOG: An Open-Source Framework for Real-Time, Accurate 3D Gaze Tracking with Deep Learning.Digital biomarkersArticle
- Eye tracking as a diagnostic tool in Alzheimer's disease, mild cognitive impairment, and related dementias: a systematic review.Alzheimer's & dementia (Amsterdam, Netherlands)Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review delineates the ocular motor disturbances across a spectrum of neurodegenerative disorders, including Alzheimer's Disease (AD) and related disorders (ADRD), Parkinson's Disease (PD), atypical parkinsonism, and others, leveraging advancements in eye-tracking technology for enhanced diagnostic precision. We delve into the different classes of eye movements, their clinical assessment, and specific abnormalities manifesting in these diseases, highlighting the nuanced differences and shared patterns. For instance, AD and ADRD are characterized by increased saccadic latencies and instability in fixation, while PD features saccadic hypometria and mild smooth pursuit impairments. Atypical parkinsonism, notably Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS), presents with distinct ocular motor signatures such as vertical supranuclear gaze palsy and saccadic apraxia, respectively. Our review underscores the diagnostic value of eye movement analysis in differentiating between these disorders and also posits the existence of underlying common pathological mechanisms. We discuss how eye movements have potential as biomarkers for neurodegenerative diseases but also some of the existing limitations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.