Evidence map›Paper›PMID 38617365›Full record

ArticlebioRxiv : the preprint server for biology2024

A conserved function of corepressors is to nucleate assembly of the transcriptional preinitiation complex.

Alexander R Leydon, Benjamin Downing, Janet Solano Sanchez, Raphael Loll-Krippleber, Nathan M Belliveau, Ricard A Rodriguez-Mias, Andrew Bauer, Isabella J Watson, Lena Bae, Judit Villén and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Alexander R LeydonDepartment of Biology, University of Washington, Seattle, 98195, USA.ORCID 0000-0003-3034-1482
Benjamin DowningDepartment of Biology, University of Washington, Seattle, 98195, USA.ORCID 0000-0002-6654-8947
Janet Solano SanchezDepartment of Biology, University of Washington, Seattle, 98195, USA.ORCID 0009-0009-2125-2550
Raphael Loll-KrippleberDepartment of Biochemistry and Donnelly Centre, University of Toronto, Toronto, Ontario, CA.
Nathan M BelliveauDepartment of Biology, University of Washington, Seattle, 98195, USA.ORCID 0000-0002-1536-1963
Ricard A Rodriguez-MiasDepartment of Genome Sciences, University of Washington, Seattle, 98195, USA.ORCID 0000-0001-7960-6387
Andrew BauerDepartment of Biology, University of Washington, Seattle, 98195, USA.
Isabella J WatsonDepartment of Biology, University of Washington, Seattle, 98195, USA.
Lena BaeDepartment of Biology, University of Washington, Seattle, 98195, USA.
Judit VillénDepartment of Genome Sciences, University of Washington, Seattle, 98195, USA.ORCID 0000-0002-1005-1739
Grant W BrownDepartment of Biochemistry and Donnelly Centre, University of Toronto, Toronto, Ontario, CA.ORCID 0000-0002-9002-5003
Jennifer L NemhauserDepartment of Biology, University of Washington, Seattle, 98195, USA.ORCID 0000-0002-8909-735X

Funding

Control of protein degradation dynamics in the auxin responseR01GM107084 · NIGMS · UNIVERSITY OF WASHINGTON · PI NEMHAUSER, JENNIFER L · 2014 to 2022
$2.4M
Towards a comprehensive roadmap of cellular signaling.R35GM119536 · NIGMS · UNIVERSITY OF WASHINGTON · PI VILLEN, JUDIT · 2016 to 2020
$2.2M
Control of protein degradation and transcriptional dynamics in the auxin responseR35GM148135 · NIGMS · UNIVERSITY OF WASHINGTON · PI JENNIFER L NEMHAUSER · 2023 to 2026
$1.5M
The role of phosphorylation in the cellular organization of the proteomeR35GM152061 · NIGMS · UNIVERSITY OF WASHINGTON · PI Judit Villen · 2024 to 2026
$1.3M
A Functional Genomics Approach to Uncover the Mechanisms of Neutrophil Galvanotaxis.K99GM147355 · NIGMS · UNIVERSITY OF WASHINGTON · PI BELLIVEAU, NATHAN M · 2022 to 2023
$225k
NIGMS NIH HHS K99 GM147355NIGMS NIH HHS R01 GM107084NIGMS NIH HHS R35 GM119536NIGMS NIH HHS R35 GM148135NIGMS NIH HHS R35 GM152061
6 · The paper itself

Abstract

The plant corepressor TPL is recruited to diverse chromatin contexts, yet its mechanism of repression remains unclear. Previously, we have leveraged the fact that TPL retains its function in a synthetic transcriptional circuit in the yeast model

Indexed as

CorepressorsDSIFIntegrasesproximity labelingReporter Synthetic Genetic ArraySPT4/SPT5 complexSPT6TAF5TFIIDTOPLESS (TPL)Transcription initiation

Identifiers

PMID38617365
PMCPMC11014602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.