Evidence map›Paper›PMID 38617257›Full record

ArticlebioRxiv : the preprint server for biology2024

Mosquito immune cells enhance dengue and Zika virus dissemination in

David R Hall, Rebecca M Johnson, Hyeogsun Kwon, Zannatul Ferdous, S Viridiana Laredo-Tiscareño, Bradley J Blitvich, Doug E Brackney, Ryan C Smith

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

David R HallInterdepartmental Program in Genetics and Genomics, Iowa State University, Ames, Iowa.
Rebecca M JohnsonCenter for Vector-Borne and Zoonotic Diseases, Department of Entomology, The Connecticut Agricultural Experiment Station, New Haven, Connecticut.
Hyeogsun KwonDepartment of Plant Pathology, Entomology and Microbiology, Iowa State University, Ames, Iowa.ORCID 0000-0002-4141-4061
Zannatul FerdousCenter for Vector-Borne and Zoonotic Diseases, Department of Entomology, The Connecticut Agricultural Experiment Station, New Haven, Connecticut.
S Viridiana Laredo-TiscareñoDepartment of Veterinary Microbiology and Preventative Medicine, Iowa State University, Ames, Iowa.
Bradley J BlitvichDepartment of Veterinary Microbiology and Preventative Medicine, Iowa State University, Ames, Iowa.ORCID 0000-0002-9857-5755
Doug E BrackneyCenter for Vector-Borne and Zoonotic Diseases, Department of Entomology, The Connecticut Agricultural Experiment Station, New Haven, Connecticut.ORCID 0000-0002-6486-3134
Ryan C SmithDepartment of Plant Pathology, Entomology and Microbiology, Iowa State University, Ames, Iowa.ORCID 0000-0003-0245-2265
Iowa State University · USConnecticut Agricultural Experiment Station · US

Funding

Implications of sequential bloodmeals on arbovirus transmission by mosquitoesR01AI148477 · NIAID · CONNECTICUT AGRICULTURAL EXPERIMENT STA · PI ARMSTRONG, PHILIP M., BRACKNEY, DOUGLAS E. · 2020 to 2024
$1.5M
The role of hemocytes in mosquito arbovirus infectionR21AI149118 · NIAID · IOWA STATE UNIVERSITY · PI SMITH, RYAN C. · 2020 to 2021
$414k
NIAID NIH HHS R01 AI148477NIAID NIH HHS R21 AI149118
6 · The paper itself

Abstract

Mosquito-borne viruses cause more than 400 million annual infections and place over half of the world's population at risk. Despite this importance, the mechanisms by which arboviruses infect the mosquito host and disseminate to tissues required for transmission are not well understood. Here, we provide evidence that mosquito immune cells, known as hemocytes, play an integral role in the dissemination of dengue virus (DENV) and Zika virus (ZIKV) in the mosquito

Identifiers

PMID38617257
PMCPMC11014501
OpenAlexW4393986555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.