Evidence map›Paper›PMID 38617250›Full record

ArticlebioRxiv : the preprint server for biology2024

Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes.

Miguel Vasconcelos Almeida, Moritz Blumer, Chengwei Ulrika Yuan, Pío Sierra, Jonathan L Price, Fu Xiang Quah, Aleksandr Friman, Alexandra Dallaire, Grégoire Vernaz, Audrey L K Putman and 7 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 4 countries.

Miguel Vasconcelos AlmeidaDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1GA, UK.ORCID 0000-0002-4816-3111
Moritz BlumerDepartment of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK.ORCID 0000-0002-5775-1767
Chengwei Ulrika YuanDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1GA, UK.ORCID 0009-0003-3875-2320
Pío SierraDepartment of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK.ORCID 0000-0003-2754-5054
Jonathan L PriceDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1GA, UK.ORCID 0000-0001-6554-5667
Fu Xiang QuahDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1GA, UK.ORCID 0000-0002-4616-5324
Aleksandr FrimanNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Alexandra DallaireDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1GA, UK.ORCID 0000-0003-1097-7766
Grégoire VernazWellcome/CRUK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN, UK.ORCID 0000-0001-8942-2370
Audrey L K PutmanDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1GA, UK.ORCID 0000-0001-5889-5095
Alan M SmithSchool of Natural Sciences, University of Hull, Hull, HU6 7RX, UK.
Domino A JoyceSchool of Natural Sciences, University of Hull, Hull, HU6 7RX, UK.
Falk ButterInstitute of Molecular Biology (IMB), Quantitative Proteomics, Ackermannweg 4, Mainz, 55128, Germany.ORCID 0000-0002-7197-7279
Astrid D HaaseNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0003-1120-9013
Richard DurbinDepartment of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK.ORCID 0000-0002-9130-1006
M Emília SantosDepartment of Zoology, University of Cambridge, Downing Street, Cambridge, CB2 3EJ, UK.ORCID 0000-0003-3158-7935
Eric A MiskaDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1GA, UK.ORCID 0000-0002-4450-576X
University of Cambridge · GBNational Institutes of Health · USUniversity of Hull · GBFriedrich-Loeffler-Institut · DEUniversity of Basel · CH

Funding

PIWI proteins and PIWI-interacting small RNAs guard the genomic integrity of germ cellsZIADK075111 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI HAASE, ASTRID · 2015 to 2025
$14.7M
Intramural NIH HHS ZIA DK075111Wellcome Trust
6 · The paper itself

Abstract

East African cichlid fishes have diversified in an explosive fashion, but the (epi)genetic basis of the phenotypic diversity of these fishes remains largely unknown. Although transposable elements (TEs) have been associated with phenotypic variation in cichlids, little is known about their transcriptional activity and epigenetic silencing. Here, we describe dynamic patterns of TE expression in African cichlid gonads and during early development. Orthology inference revealed an expansion of

Identifiers

PMID38617250
PMCPMC11014572
OpenAlexW4393444553

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.