Evidence map›Paper›PMID 38616489›Full record

ArticlePlant communications2024

Stress Knowledge Map: A knowledge graph resource for systems biology analysis of plant stress responses.

Carissa Bleker, Živa Ramšak, Andras Bittner, Vid Podpečan, Maja Zagorščak, Bernhard Wurzinger, Špela Baebler, Marko Petek, Maja Križnik, Annelotte van Dieren and 7 more

Abstract read
In one paragraph

Article in Plant communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. With or without a CaPlanta · 2025
    Article
  7. Article
  8. Evaluating plant growth-defense trade-offs by modeling the interaction between primary and secondary metabolism.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. CaBMC plant biology · 2025
    Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Carissa BlekerDepartment of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 121, 1000 Ljubljana, Slovenia. Electronic address: carissa.bleker@nib.si.
Živa RamšakDepartment of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 121, 1000 Ljubljana, Slovenia.
Andras BittnerPlant Cell Biology, Institute of Cellular and Molecular Botany, University of Bonn, Kirschallee 1, 53115 Bonn, Germany.
Vid PodpečanDepartment of Knowledge Technologies, Jožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia.
Maja ZagorščakDepartment of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 121, 1000 Ljubljana, Slovenia.
Bernhard WurzingerDepartment of Functional & Evolutionary Ecology, University of Vienna, Djerassiplatz 1, 1030 Vienna, Austria.
Špela BaeblerDepartment of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 121, 1000 Ljubljana, Slovenia.
Marko PetekDepartment of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 121, 1000 Ljubljana, Slovenia.
Maja KrižnikDepartment of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 121, 1000 Ljubljana, Slovenia.
Annelotte van DierenPlant Cell Biology, Institute of Cellular and Molecular Botany, University of Bonn, Kirschallee 1, 53115 Bonn, Germany.
Juliane GruberDepartment of Functional & Evolutionary Ecology, University of Vienna, Djerassiplatz 1, 1030 Vienna, Austria.
Leila Afjehi-SadatMass Spectrometry Unit, Core Facility Shared Services, University of Vienna, Djerassiplatz 1, 1030 Vienna, Austria.
Wolfram WeckwerthDepartment of Functional & Evolutionary Ecology, University of Vienna, Djerassiplatz 1, 1030 Vienna, Austria.
Anže ŽupaničDepartment of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 121, 1000 Ljubljana, Slovenia.
Markus TeigeDepartment of Functional & Evolutionary Ecology, University of Vienna, Djerassiplatz 1, 1030 Vienna, Austria.
Ute C VothknechtPlant Cell Biology, Institute of Cellular and Molecular Botany, University of Bonn, Kirschallee 1, 53115 Bonn, Germany.
Kristina GrudenDepartment of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 121, 1000 Ljubljana, Slovenia. Electronic address: kristina.gruden@nib.si.

Funding

Non-US Government Research Support type
6 · The paper itself

Abstract

Stress Knowledge Map (SKM; https://skm.nib.si) is a publicly available resource containing two complementary knowledge graphs that describe the current knowledge of biochemical, signaling, and regulatory molecular interactions in plants: a highly curated model of plant stress signaling (PSS; 543 reactions) and a large comprehensive knowledge network (488 390 interactions). Both were constructed by domain experts through systematic curation of diverse literature and database resources. SKM provides a single entry point for investigations of plant stress response and related growth trade-offs, as well as interactive explorations of current knowledge. PSS is also formulated as a qualitative and quantitative model for systems biology and thus represents a starting point for a plant digital twin. Here, we describe the features of SKM and show, through two case studies, how it can be used for complex analyses, including systematic hypothesis generation and design of validation experiments, or to gain new insights into experimental observations in plant biology.

Indexed as

PlantsStress, PhysiologicalSystems BiologyDatabases, FactualPlant Physiological PhenomenaSignal Transductionknowledge graphplant digital twinplant signalingplant stress responsessystems biology

Identifiers

PMID38616489
PMCPMC11211517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.