Evidence map›Paper›PMID 38616366›Full record

ArticleThe Journal of frailty & aging2024

New Perspectives in the Association between Anthropometry and Mortality: The Role of Calf Circumference.

C Ceolin, V Acunto, C Simonato, S Cazzavillan, M Vergadoro, M V Papa, G S Trapella, R Sermasi, M Noale, M De Rui and 6 more

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Article in The Journal of frailty & aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

C CeolinChiara Ceolin, Department of Medicine (DIMED), Geriatrics Division, University of Padua, Via Giustiniani 2, 35128 Padua, Italy, Fax: +39 049 8211218; Phone: +39 049 8218949, E-mail: chiara.ceolin.1@gmail.com.
V Acunto
C Simonato
S Cazzavillan
M Vergadoro
M V Papa
G S Trapella
R Sermasi
M Noale
M De Rui
B M Zanforlini
C Curreri
A Bertocco
M Devita
A Coin
G Sergi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsConsidering the impact of sarcopenia on mortality, and the difficulty to assessment of body composition, the hypothesis of the study is that calf circumference (CC) is closely related to mortality in older patients. The aim of the study was to analyze the potential role of CC to predict mortality in old individuals at 3, 6 and 12 months after discharge from hospital.

methodsPatients aged >65 years were recruited for this retrospective study from September 2021 to March 2022. Their physical and body composition characteristics (including Body Mass Index-BMI and Mini Nutritional Assessment-MNA) were measured; data on mortality at 3 (T3), 6 (T6) and 12 (T12) months after discharge were recorded. Sarcopenia was diagnosed according to the 2019 European Consensus criteria.

resultsParticipants were 192 older adults (92 women), with a mean age of 82.8±7.0 years. Sarcopenic people were 41. The mortality rate was higher in sarcopenic people only at T3 and T6. CC had comparable validity in predicting mortality to that of MNA and ASMMI (Appendicular Skeletal Muscle Mass), and was better than BMI and serum albumin at each time point. Youden's index showed that the best cut-off for CC for predicting mortality was 30.6 cm both at T3 (sensitivity: 74%; specificity: 75%) and T6 (sensitivity: 75%; specificity: 67%). At the Cox regression model for mortality, high values of CC (HR 0.73, CI95% 0.60-0.89/p<0.001) and ADL scores (HR 0.72, CI95% 0.54-0.96/p=0.04) were protective factors at T6 and T12 respectively; at T12 high comorbidity rate was a risk factor (HR 1.28, IC95% 1.02-1.62/p=0.04).

conclusionsCC has a validity comparable to MNA and ASMMI in predicting mortality at 3, 6 and 12 months after hospital discharge. Moreover, it can be considered an independent predictor of medium-term mortality in the hospitalized older population. CC can be an effective method for the prognostic stratification of these patients, due to its simplicity and immediacy.

Indexed as

SarcopeniaAgedAged, 80 and overAnthropometryBody CompositionBody Mass IndexFemaleHumansRetrospective Studiescalf circumferencehospitalizationmortalityOlder adultssarcopenia

Identifiers

PMID38616366
PMCPMC12275705

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.