Evidence map›Paper›PMID 38616194›Full record

ArticleDevelopment genes and evolution2024

Identification and characterization of the Dmrt1B gene in the oriental river prawn, Macrobrachium nipponense.

Gang Jiang, Yucai Xue, Arifuzzaman Arifuzzaman, Xuxiong Huang

Open access · bronzeAbstract read
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In one paragraph

Article in Development genes and evolution, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Gang JiangCentre for Research On Environmental Ecology and Fish Nutrition (CREEFN) of the Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China.
Yucai XueCentre for Research On Environmental Ecology and Fish Nutrition (CREEFN) of the Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China.
Arifuzzaman ArifuzzamanCentre for Research On Environmental Ecology and Fish Nutrition (CREEFN) of the Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China.
Xuxiong HuangCentre for Research On Environmental Ecology and Fish Nutrition (CREEFN) of the Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, 201306, China. xxhuang@shou.edu.cn.
Ministry of Agriculture and Rural Affairs · CNMinistry of Agriculture · BW

Funding

the project of National Key Research and Development Program of China 2022YFE0203900
6 · The paper itself

Abstract

Dmrt (doublesex and mab-3 related transcription factor) is a protein family of transcription factors implicated in sexual regulation. Dmrt proteins are widely conserved and known for their involvement in sex determination and differentiation across species, from invertebrates to humans. In this study, we identified a novel gene with a DM (doublesex/Mab-3)-domain gene in the river prawn, Macrobrachium nipponense, which we named MniDmrt1B due to its similarities and close phylogenetic relationship with Dmrt1B in Macrobrachium rosenbergii. Through amino acid alignments and structural predictions, we observed conservation and identified putative active sites within the DM domain. qRT-PCR analysis revealed that MniDmrt1B exhibited high expression levels in the testis, with consistently higher expression in males compared to females during development. Additionally, similar to other sex-regulated genes, the MniDmrt1B gene exhibited high expression levels during the sex differentiation-sensitive periods in M. nipponense. These results strongly indicated that MniDmrt1B probably plays an important role in testis development and sex differentiation in M. nipponense.

Indexed as

Arthropod ProteinsPalaemonidaeTranscription FactorsAmino Acid SequenceAnimalsFemaleGene Expression Regulation, DevelopmentalMalePhylogenySequence AlignmentSex DifferentiationTestisArthropod ProteinsDMRT1 proteinTranscription FactorsMacrobrachium nipponenseMniDmrt1BqRT-PCRSex differentiationTemporal and spatial expression

Identifiers

PMID38616194
OpenAlexW4394817311

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.