Evidence map›Paper›PMID 38615158›Full record

ArticleInternational journal of obesity (2005)2024

Visceral-to-peripheral adiposity ratio: a critical determinant of sex and ethnic differences in cardiovascular risks among Asian Indians and African Creoles in Mauritius.

Vinaysing Ramessur, Sadhna Hunma, Noorjehan Joonas, Bibi Nasreen Ramessur, Yves Schutz, Jean-Pierre Montani, Abdul G Dulloo

Open access · hybridAbstract read
In one paragraph

Article in International journal of obesity (2005), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Vinaysing RamessurObesity Research Unit, Biochemistry Dept., Central Health Laboratory, Victoria Hospital, Ministry of Health & Wellness, Plaines Wilhems, Mauritius.
Sadhna HunmaObesity Research Unit, Biochemistry Dept., Central Health Laboratory, Victoria Hospital, Ministry of Health & Wellness, Plaines Wilhems, Mauritius.
Noorjehan JoonasObesity Research Unit, Biochemistry Dept., Central Health Laboratory, Victoria Hospital, Ministry of Health & Wellness, Plaines Wilhems, Mauritius.
Bibi Nasreen RamessurObesity Research Unit, Biochemistry Dept., Central Health Laboratory, Victoria Hospital, Ministry of Health & Wellness, Plaines Wilhems, Mauritius.
Yves SchutzDepartment of Endocrinology, Metabolism & Cardiovascular System, Faculty of Science & Medicine, University of Fribourg, Fribourg, Switzerland.
Jean-Pierre MontaniDepartment of Endocrinology, Metabolism & Cardiovascular System, Faculty of Science & Medicine, University of Fribourg, Fribourg, Switzerland.
Abdul G DullooDepartment of Endocrinology, Metabolism & Cardiovascular System, Faculty of Science & Medicine, University of Fribourg, Fribourg, Switzerland. abdul.dulloo@alumni.unifr.ch.ORCID 0000-0003-3877-6149
University of Fribourg · CHMinistry of Health and Quality of Life · MU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsCoronary heart disease morbidity and mortality are higher in people of South Asian origin than in those of African origin. We investigated whether as young adults without diabetes, people in Mauritius of South Asian descent (Indians) would show a more adverse cardiovascular risk profile that those of predominantly African descent (Creoles), and whether this could be explained by ethnic differences in visceral adiposity or other fat distribution patterns.

methodsThe study was conducted in 189 young non-physically active adults, with the following measurements conducted after an overnight fast: anthropometry (weight, height, waist circumference), whole-body and regional body composition by dual-energy x-ray absorptiometry, blood pressure, and blood assays for glycemic (glucose and HbA1c) and lipid profile (triglycerides and cholesterols).

resultsThe results indicate higher serum triglycerides and lower HDL cholesterol in men than in women, and in Indians than in Creoles (p < 0.001). No significant differences due to sex or ethnicity are observed in body mass index and waist circumference, but indices of visceral adiposity (visceral/android, visceral/subcutaneous) and visceral-to-peripheral adiposity ratio (visceral/gynoid, visceral/limb) were significantly higher in men than in women, and in Indians than in Creoles. The significant effects of sex and ethnicity on blood lipid profile were either completely abolished or reduced to a greater extent after adjusting for the ratio of visceral-to-peripheral adiposity than for visceral adiposity per se.

conclusionsIn young adults in Mauritius, Indians show a more adverse pattern of body fat distribution and blood lipid risk profile than Creoles. Differences in their fat distribution patterns, however, only partially explain their differential atherogenic lipid risk profile, amid a greater impact of visceral-to-peripheral adiposity ratio than that of visceral adiposity per se on sex and ethnic differences in cardiovascular risks; the former possibly reflecting the ratio of hazardous (visceral) adiposity and protective (peripheral) superficial subcutaneous adiposity.

Indexed as

AdiposityBlack PeopleCardiovascular DiseasesIntra-Abdominal FatAdultAfrican PeopleAsian PeopleBody Mass IndexFemaleHeart Disease Risk FactorsHumansIndiaMaleMauritiusNorth American PeopleRisk Factors

Identifiers

PMID38615158
PMCPMC11281908
OpenAlexW4394783333

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.