Evidence map›Paper›PMID 38615153›Full record

ArticleScientific reports2024

Simulation of daily soft multifocal contact lenses using SimVis Gekko: from in-vitro and computational characterization to clinical validation.

Eduardo Esteban-Ibañez, Diego Montagud-Martínez, Lucie Sawides, Amal Zaytouny, Alberto de Castro, Irene Sisó-Fuertes, Xoana Barcala, David P Piñero, Walter D Furlan, Carlos Dorronsoro and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Halo Measurements in Simulated Multifocal Intraocular Lenses.Translational vision science & technology · 2026
    Article
  2. Article
  3. In vivo assessment of multifocal contact lens fitting using anterior segment optical coherence tomography.Contact lens & anterior eye : the journal of the British Contact Lens Association · 2025
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eduardo Esteban-Ibañez2EyesVision SL, Plaza de la Encina, 10, Nucleo 3, Planta 4ª, 28760, Tres Cantos, Madrid, Spain. eesteban@2eyesvision.com.
Diego Montagud-MartínezCentro de Tecnologías Físicas, Universitat Politècnica de València, Valencia, Spain.
Lucie Sawides2EyesVision SL, Plaza de la Encina, 10, Nucleo 3, Planta 4ª, 28760, Tres Cantos, Madrid, Spain.
Amal ZaytounyInstitute of Optics 'Daza de Valdés', Spanish National Research Council, IO-CSIC, Madrid, Spain.
Alberto de CastroInstitute of Optics 'Daza de Valdés', Spanish National Research Council, IO-CSIC, Madrid, Spain.
Irene Sisó-Fuertes2EyesVision SL, Plaza de la Encina, 10, Nucleo 3, Planta 4ª, 28760, Tres Cantos, Madrid, Spain.
Xoana Barcala2EyesVision SL, Plaza de la Encina, 10, Nucleo 3, Planta 4ª, 28760, Tres Cantos, Madrid, Spain.
David P PiñeroDepartamento de Óptica, Farmacología y Anatomía, Universidad de Alicante, Alicante, Spain.
Walter D FurlanDepartamento de Óptica y Optometría y Ciencias de la Visión, Universitat de València, Valencia, Spain.
Carlos Dorronsoro2EyesVision SL, Plaza de la Encina, 10, Nucleo 3, Planta 4ª, 28760, Tres Cantos, Madrid, Spain.
Enrique Gambra2EyesVision SL, Plaza de la Encina, 10, Nucleo 3, Planta 4ª, 28760, Tres Cantos, Madrid, Spain.

Funding

Comunidad de Madrid IND2020/BMD-17442Ministerio de Ciencia, Innovación y Universidades CPP2021-008388Ministerio de Ciencia, Innovación y Universidades PTQ2021-011963Ministerio de Ciencia, Innovación y Universidades RYC2021-033355-IMinisterio de Universidades Margarita Salas
6 · The paper itself

Abstract

Multifocal contact lenses (MCLs) are one of the solutions to correct presbyopia, but their adoption is not widespread. To address this situation, visual simulators can be used to refine the adaptation process. This study aims to obtain accurate simulations for a visual simulator (SimVis Gekko; 2EyesVision) of daily soft MCL designs from four manufacturers. In-vitro characterization of these MCLs-several powers and additions- was obtained using NIMO TR-1504. From the averaged relative power profiles across powers, phase maps were reconstructed and the Through-Focus Visual Strehl metric was calculated for each MCL design. The SimVis Gekko simulation corresponding to each MCL design was obtained computationally and bench-validated. Finally, the MCL simulations were clinically validated involving presbyopic patients. The clinical validation results show a good agreement between the SimVis Gekko simulations and the real MCLs for through-focus visual acuity (TF-VA) curves and VA at three real distances. All MCL designs showed a partial correlation higher than 0.90 and a Root Mean Square Error below 0.07 logMAR between the TF-VA of simulations and Real MCLs across subjects. The validity of the simulation approach using SimVis Gekko and in-vitro measurements was confirmed in this study, opening the possibility to accelerate the adaptation of MCLs.

Indexed as

Contact Lenses, HydrophilicLizardsPresbyopiaAnimalsComputer SimulationHumansVisual Acuity

Identifiers

PMID38615153
PMCPMC11016090

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.