Evidence map›Paper›PMID 38614471›Full record

ArticleEuropean journal of public health2024

Educational inequalities in major depressive disorder prevalence, timing and duration among adults over the life course: a microsimulation analysis based on the Lifelines Cohort Study.

Alexander Lepe, Liza A Hoveling, Michaël Boissonneault, Joop A A de Beer, Sijmen A Reijneveld, Marlou L A de Kroon, Aart C Liefbroer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Alexander LepeDepartment of Health Sciences, Community and Occupational Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-7593-4770
Liza A HovelingDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Michaël BoissonneaultNetherlands Interdisciplinary Demographic Institute (NIDI)-KNAW, University of Groningen, The Hague, The Netherlands.
Joop A A de BeerNetherlands Interdisciplinary Demographic Institute (NIDI)-KNAW, University of Groningen, The Hague, The Netherlands.
Sijmen A ReijneveldDepartment of Health Sciences, Community and Occupational Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Marlou L A de KroonDepartment of Health Sciences, Community and Occupational Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Aart C LiefbroerDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
University Medical Center Groningen · NLUniversity of Groningen · NL

Funding

The Netherlands Organization for Health Research and Development 531003011The Netherlands Organization for Health Research and Development ZonMw
6 · The paper itself

Abstract

backgroundEducational inequalities in major depressive disorder (MDD) pose a major challenge. Tackling this issue requires evidence on the long-term impact of intervening on modifiable factors, for example lifestyle and psychosocial factors. For this reason, we aimed to simulate the development of educational inequalities in MDD across the life course, and to estimate the potential impact of intervening on modifiable factors.

methodsWe used data from the prospective Dutch Lifelines Cohort Study to estimate the required input for a continuous-time microsimulation. The microsimulation allowed us to project the development of educational inequalities in MDD between ages 18 and 65, and to assess the potential benefit of intervening on quality of social contacts, health literacy and smoking.

resultsOn average, an additional 19.1% of individuals with low education will ever experience MDD between ages 18 and 65 compared with those with high education. Additionally, individuals with low education generally will develop MDD 0.9 years earlier and spend 1.2 years more with MDD, than individuals with high education. Improving the quality of social contacts in individuals with low education produced the largest effect; it would reduce the inequalities in the prevalence, onset and duration of MDD by an average of 18.4%, 18.3% and 28.6%, respectively.

conclusionsIntervening on modifiable factors, particularly quality of social contacts, in individuals with low education could help reduce the estimated educational inequalities in MDD over the life course.

Indexed as

Educational StatusMajor Depressive DisorderAdolescentAdultAgedCohort StudiesComputer SimulationFemaleHealth Status DisparitiesHumansMaleMiddle AgedNetherlandsPrevalenceProspective StudiesSocioeconomic Factors

Identifiers

PMID38614471
PMCPMC11293816
OpenAlexW4394793387

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.