Evidence map›Paper›PMID 38614193›Full record

ArticleAmerican journal of ophthalmology2024

Biomechanics Explains Variability of Response of Small Hypertropia to Graded Vertical Rectus Tenotomy.

Chang Zoo Kim, Seongjin Lim, Joseph L Demer

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Chang Zoo KimFrom the Stein Eye Institute and Department of Ophthalmology, University of California, Los Angeles (C.K., S.L., J.L.D.), Los Angeles, California, USA; Department of Ophthalmology, College of Medicine, Kosin University (C.K.), Busan, Korea.
Seongjin LimFrom the Stein Eye Institute and Department of Ophthalmology, University of California, Los Angeles (C.K., S.L., J.L.D.), Los Angeles, California, USA.
Joseph L DemerFrom the Stein Eye Institute and Department of Ophthalmology, University of California, Los Angeles (C.K., S.L., J.L.D.), Los Angeles, California, USA; Department of Neurology, University of California, Los Angeles (J.L.D.), Los Angeles, California, USA; Bioengineering Department, University of California, Los Angeles (J.L.D.), Los Angeles, California, USA. Electronic address: jld@jsei.ucla.edu.
University of California, Los Angeles · US

Funding

Vision Research Core at UCLAP30EY000331 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Xian-Jie Yang · 1985 to 2026
$16.8M
BIOMECHANICAL ANALYSIS IN STRABISMUS SURGERYR01EY008313 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOSEPH Louis DEMER · 1991 to 2026
$15.0M
SEARCH FOR NEW GENES IN FAMILIES WITH EPISODIC VERTIGO AND ATAXIAP50DC005224 · NIDCD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BALOH, ROBERT WILLIAM · 2002 to 2006
$7.5M
Data-Driven Biomechanical Simulation of Eye Movement and StrabismusR01EY029715 · NEI · GEORGE MASON UNIVERSITY · PI WEI, QI · 2019 to 2022
$1.5M
NEI NIH HHS P30 EY000331NEI NIH HHS R01 EY008313NEI NIH HHS R01 EY029715NIDCD NIH HHS P50 DC005224
6 · The paper itself

Abstract

purposeSmall angle hypertropia in sagging eye syndrome is conveniently treated by graded vertical rectus tenotomy, yet an adjustable technique under topical anesthesia has been recommended because of variability of effect. We performed graded tenotomy in an experimental model to elucidate the reason for variability of response to this surgical procedure.

designExperimental study.

methodsThirty-two fresh bovine rectus musculotendon specimens were prepared including continuity with insertional sclera, and extending for a total 40 mm length to the proximal muscle bellies, and trimmed to 16 mm width. Specimens were anchored by the clamps at the scleral insertion and muscle belly ends within a physiological chamber. After preconditioning and elongation to 10% strain was imposed by a linear motor, tensile force was allowed to stabilize at a plateau state. Then 25%, 50%, 75%, 90%, and 100% marginal tenotomies were performed progressively as remnant forces were measured.

resultsTendon thickness averaged 0.29 ± 0.05 mm and width 19.71 ± 2.25 mm. On average, remnant force decreased linearly (R

conclusionOn average, there is a linear relationship between graded rectus tenotomy and percentage force reduction, but the effect among individual tendons is large, paralleling the reported variation in surgical effect. This explains and implies continued advisability of adjustable technique in this procedure.

Indexed as

Oculomotor MusclesStrabismusTendonsTenotomyAnimalsBiomechanical PhenomenaCattle

Identifiers

PMID38614193
PMCPMC11415607
OpenAlexW4394757100

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.