Evidence map›Paper›PMID 38613256›Full record

SynthesisSchizophrenia bulletin2024

Long-term Changes in Personal Recovery and Quality of Life Among Patients With Schizophrenia Spectrum Disorders and Different Durations of Illness: A Meta-analysis.

Lars de Winter, Auke Jelsma, Jentien M Vermeulen, Jaap van Weeghel, Ilanit Hasson-Ohayon, Cornelis L Mulder, Nynke Boonstra, Wim Veling, Lieuwe de Haan

Abstract readMeta-Analysis
In one paragraph

Synthesis in Schizophrenia bulletin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lars de WinterPhrenos Center of Expertise, Utrecht, the Netherlands.
Auke JelsmaDepartment of Psychiatry, Amsterdam UMC location AMC, Amsterdam, the Netherlands.
Jentien M VermeulenDepartment of Psychiatry, Amsterdam UMC location AMC, Amsterdam, the Netherlands.
Jaap van WeeghelTranzo, Tilburg University, Tilburg, the Netherlands.
Ilanit Hasson-OhayonDepartment of Psychology, Bar-Ilan University, Ramat-Gan, Israel.
Cornelis L MulderEpidemiological and Social Psychiatric Research Institute, Erasmus Medical Center, Rotterdam, the Netherlands.
Nynke BoonstraNHL Stenden University of Applied Science, Leeuwarden, the Netherlands.
Wim VelingUniversity of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Lieuwe de HaanDepartment of Psychiatry, Amsterdam UMC location AMC, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and hypothesisIn schizophrenia spectrum disorders (SSD) personal recovery and subjective quality of life (S-QOL) are crucial and show conceptual overlap. There is limited knowledge about how these outcomes change over time. Therefore, we investigated changes in personal recovery or S-QOL for patients with SSD. We specifically focused on the influence of the patients' durations of illness (DOI) on changes in personal recovery and S-QOL. STUDY

designWe included 46 studies investigating longitudinal changes in quantitative assessments of personal recovery or S-QOL for patients with SSD. Outcomes were categorized in overall personal recovery, overall S-QOL connectedness, hope and optimism, identity, meaning in life, and empowerment. We evaluated effect sizes of change between baseline and follow-up assessments. We also evaluated potential moderating effects, including DOI on these changes in outcomes. STUDY

resultsWe found small improvements of overall personal recovery and S-QOL, but marginal or no improvement over time in the other more specific outcome domains. Patients without a schizophrenia diagnosis, a younger age, and more recent publications positively influenced these changes. We found no significant influence of DOI on the changes in any outcome domain.

conclusionsImprovement in personal recovery or S-QOL of people with SSD is modest at best. However, these studies did not fully capture the personal narratives or nonlinear process of recovery of an individual. Future research should focus on how to shift from a clinical to more person-oriented approach in clinical practice to support patients in improving their personal process of recovery. REVIEW PROTOCOL REGISTRATION: CRD42022377100.

Indexed as

Quality of LifeSchizophreniaAdultHumansMental Health RecoveryOutcome Assessment, Health CarePsychotic DisordersTime Factorschangescoursemeta-analysispersonal recoverypsychosisschizophrenia spectrum disorderssubjective quality of life

Identifiers

PMID38613256
PMCPMC11661942

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.