Evidence map›Paper›PMID 38613111›Full record

ArticleNutrients2024

Online Questionnaire with Fibromyalgia Patients Shows Negative Correlations between Disease Severity and Adherence to Mediterranean Diet.

Elisa Proietti, Fabio Rapallo, Elena Molinari, Viviana Mucci, Lucio Marinelli, Consuelo Borgarelli, Bruno Burlando, Livia Pisciotta, Ilaria Demori

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07517757 (Impact of Different Dietary Strategies in the Management of Overweight and Obesity in Patients With Fibromyalgia), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07517757 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Impact of Different Dietary Strategies in the Management of Overweight and Obesity in Patients With Fibromyalgia: Effects on Pain, Disease Severity, Nutritional and Metabolic Profile, Gut Microbiota and Microbial Metabolites, and Brain GABA and Glutamate Levels

TypeinterventionalSponsorUniversita degli Studi di GenovaRan2026 to 2028Enrolled90ConditionsFibromyalgia (FM)ArmsVery Low-Calorie Ketogenic Diet, Mediterranean diet, Mediterranean diet enriched by GABA-producing probiotic
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Elisa ProiettiDepartment of Internal Medicine (DIMI), University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy.ORCID 0009-0000-0204-5753
Fabio RapalloDepartment of Economics (DIEC), University of Genova, Via Vivaldi, 5, 16126 Genova, Italy.ORCID 0000-0001-6451-5140
Elena MolinariClincal Psychology Center, Division of Neurology, E.O. Ospedali Galliera, Via Mura delle Cappuccine 14, 16128 Genova, Italy.
Viviana MucciSchool of Science, Western Sydney University, Penrith, NSW 2750, Australia.
Lucio MarinelliDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genova, Largo P. Daneo 3, 16132 Genova, Italy.ORCID 0000-0003-0620-7654
Consuelo BorgarelliDepartment of Internal Medicine (DIMI), University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy.ORCID 0000-0001-8210-5604
Bruno BurlandoDepartment of Pharmacy (DIFAR), University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.ORCID 0000-0001-7545-0311
Livia PisciottaDepartment of Internal Medicine (DIMI), University of Genova, Viale Benedetto XV, 6, 16132 Genova, Italy.ORCID 0000-0001-7080-9807
Ilaria DemoriDepartment of Pharmacy (DIFAR), University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.ORCID 0000-0002-6894-8223
University of Genoa · ITOspedale Policlinico San Martino · ITEnte Ospedaliero Ospedali Galliera · ITWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibromyalgia (FM) is a multidimensional disorder in which intense chronic pain is accompanied by a variety of psychophysical symptoms that impose a burden on the patients' quality of life. Despite the efforts and the recent advancement in research, FM pathogenesis and effective treatment remain unknown. Recently, the possible role of dietary patterns and/or components has been gaining attention. The current study aimed to investigate a potential correlation between adherence to the Mediterranean diet (MedDiet) and FM severity in a sample of Italian FM patients. An online survey was designed, composed of customized questions and validated questionnaires with the aim of investigating the intensity and type of pain, the presence of other psychophysical symptoms, the overall impact of FM, general food and lifestyle habits, and adherence to the MedDiet. The collected responses were analyzed for descriptive statistics, linear regression, and propensity score analyses. The results show that, despite considerable use of pharmaceuticals and supplements, FM participants suffered from a high-severity grade disease. However, those with good adherence to the MedDiet experienced a lower pain intensity and overall FM impact. A propensity score analysis indicates a positive influence of the MedDiet against FM severity, thus unveiling the need for well-designed intervention studies to evaluate the therapeutic potential of different dietary patterns.

Indexed as

Chronic PainDiet, MediterraneanFibromyalgiaDietary SupplementsHumansPatient AcuityQuality of Lifebody mass indexdietary supplementsfood habitslifestylepain

Identifiers

PMID38613111
PMCPMC11013287
OpenAlexW4394572397

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.