Evidence map›Paper›PMID 38613057›Full record

Trial reportNutrients2024

Plasma-Induced Changes in the Metabolome Following Vistula Tart Cherry Consumption.

Emma Squires, Ian H Walshe, William Cheung, Samantha L Bowerbank, John R Dean, Jacob Wood, Malachy P McHugh, Stephan Plattner, Glyn Howatson

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Emma SquiresFaculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.ORCID 0009-0003-7194-7744
Ian H WalsheFaculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.ORCID 0000-0002-6001-7854
William CheungFaculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.
Samantha L BowerbankFaculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.ORCID 0000-0002-4685-9350
John R DeanFaculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.ORCID 0000-0001-5729-356X
Jacob WoodFaculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.
Malachy P McHughFaculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.ORCID 0000-0002-8371-8151
Stephan PlattnerIprona Lana SpA, 39011 Lana, South Tyrol, Italy.ORCID 0000-0003-1025-0284
Glyn HowatsonFaculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.ORCID 0000-0001-8494-2043
Northumbria University · GBNorthwell Health · USNorth-West University · ZA

Funding

Iprona Lana SpA RST00494
6 · The paper itself

Abstract

Evidence suggests that tart cherry (TC) supplementation has beneficial effects on health indices and recovery following strenuous exercise. However, little is known about the mechanisms and how TC might modulate the human metabolome. The aim of this study was to evaluate the influence of an acute high- and low-dose of Vistula TC supplementation on the metabolomic profile in humans. In a randomised, double-blind, placebo controlled, cross-over design, 12 healthy participants (nine male and three female; mean ± SD age, stature, and mass were 29 ± 7 years old, 1.75 ± 0.1 m, and 77.3 ± 10.5 kg, respectively) visited the laboratory on three separate occasions (high dose; HI, low dose; LO, or placebo), separated by at least seven days. After an overnight fast, a baseline venous blood sample was taken, followed by consumption of a standardised breakfast and dose conditions (HI, LO, or placebo). Subsequent blood draws were taken 1, 2, 3, 5, and 8 h post consumption. Following sample preparation, an untargeted metabolomics approach was adopted, and the extracts analysed by LCMS/MS. When all time points were collated, a principal component analysis showed a significant difference between the conditions (

Indexed as

Prunus aviumAdultBody HeightBreakfastFemaleHumansMaleMetabolomeMetabolomicsYoung Adultbioavailabilitymetabolometart cherry

Identifiers

PMID38613057
PMCPMC11013268
OpenAlexW4393388375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.