ArticleNutrients2024
Lower Geriatric Nutritional Risk Index and Prognostic Nutritional Index Predict Postoperative Prognosis in Patients with Hepatocellular Carcinoma.
Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
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Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Prognostic value of prognostic nutritional index in patients with hepatocellular carcinoma undergoing hepatectomy: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Prognostic value of Prognostic Nutritional Index in cancer: an umbrella review of systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Prognostic impact of malnutrition based on the global leadership initiative on malnutrition criteria in older patients undergoing liver resection for hepatocellular carcinoma.Surgery today · 2026Article
- Prediction of Long-Term Prognosis in Patients With Hepatocellular Carcinoma Using the National Clinical Database Risk Calculator.Annals of gastroenterological surgery · 2026Article
- Integrated assessment of preoperative nutritional, inflammatory, and metabolic biomarkers and early outcomes in geriatric hip fracture surgery: a retrospective matched study.BMC geriatrics · 2026Article
- Association between the Prognostic Nutritional Index and survival outcomes in hepatocellular carcinoma patients receiving immune checkpoint inhibitors: a systematic review and meta-analysis.Translational cancer research · 2026Review
- Association of obesity and nutritional status on early sepsis-associated acute kidney injury in older patients with sepsis.BMC nephrology · 2026Article
- Combined preoperative PNI and APRI for risk stratification after curative hepatectomy for hepatocellular carcinoma.BMC gastroenterology · 2026Article
- Predictive Value of Nutrition Indices in Advanced Hepatocellular Carcinoma Patients Treated With Lenvatinib.The Kaohsiung journal of medical sciences · 2026Article
- Preoperative low Geriatric Nutritional Risk Index increases intensive care unit admission risk in patients undergoing gastrointestinal tumor surgery.Frontiers in nutrition · 2026Article
- Post-Treatment Prognostic Nutritional Index Outperforms Baseline Index as an Independent Prognostic Biomarker in Advanced Hepatocellular Carcinoma Receiving Immune-Based Systemic Therapy.Journal of hepatocellular carcinoma · 2026Article
- Pretreatment Prognostic Nutritional Index Predicts Progression-Free Survival in BCLC Stage C Hepatocellular Carcinoma Treated with Sorafenib.Cancer management and research · 2026Article
- Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma.Oncology letters · 2026Article
- The predictive value of interleukin-2 receptor and prognostic nutritional index in patients with diffuse large B-cell lymphoma.Frontiers in medicine · 2026Article
- Efficacy and Safety of Radiotherapy Combined with PD-1 Inhibitors and Targeted Therapy for Unresectable Hepatocellular Carcinoma: A Retrospective, Real-World Multicenter Study.Journal of hepatocellular carcinoma · 2026Article
- Association of geriatric nutritional risk index with metabolic dysfunction-associated steatotic liver disease and subtypes in Chinese elderly: identification of an overnutrition risk threshold and implications for extended risk stratification.Frontiers in nutrition · 2026Article
- The Prognostic Implications of the Geriatric Nutritional Risk Index in Patients with Prostate Cancer: A Single-Center Retrospective Cohort Study.Healthcare (Basel, Switzerland) · 2025Article
- Geriatric nutritional risk index and prognostic nutritional index improves predictive value of postoperative mortality: a large-scale retrospective cohort study.Perioperative medicine (London, England) · 2025Article
- Association between prognostic nutritional index and risk of moderate-to-severe basic activities of daily living dependence two years after hip fracture surgery in older adults.BMC geriatrics · 2025Article
- A nomogram based on PNI and preoperative TACE can predict overall survival in patients with larger than 2 cm HCC after hepatectomy.Updates in surgery · 2025Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing evidence suggests that nutritional indices, including the geriatric nutritional risk index (GNRI) and prognostic nutritional index (PNI), are predictors of poor prognosis in patients with hepatocellular carcinoma (HCC). Hence, this study aimed to explore the value of the GNRI and PNI in evaluating postoperative prognosis in patients with HCC, particularly regarding its recurrence patterns. We performed a retrospective analysis of 203 patients with HCC who underwent initial hepatic resection. Patients were divided into two groups according to the GNRI (cutoff: 98) and PNI (cutoff: 45). The GNRI and PNI were significantly associated with body composition (body mass index and skeletal muscle mass index), hepatic function (Child-Pugh Score), tumor factors (tumor size and microvascular invasion), and perioperative factors (blood loss and postoperative hospitalization). Patients with a low PNI or low GNRI had significantly worse overall survival (OS) and recurrence-free survival. Patients with early recurrence had lower PNI and GNRI scores than those without early recurrence. Patients with extrahepatic recurrence had lower PNI and GNRI scores than those without extrahepatic recurrence. The PNI and GNRI might be useful in predicting the prognosis and recurrence patterns of patients with HCC after hepatic resection.
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