Evidence map›Paper›PMID 38612962›Full record

ArticleNutrients2024

The Vitamin D Receptor as a Prognostic Marker in Breast Cancer-A Cohort Study.

Linnea Huss, Igis Gulz-Haake, Emma Nilsson, Helga Tryggvadottir, Linn Nilsson, Björn Nodin, Karin Jirström, Karolin Isaksson, Helena Jernström

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Linnea HussDepartment of Clinical Sciences, Division of Oncology, Lund University, 221 85 Lund, Sweden.ORCID 0000-0002-8597-9224
Igis Gulz-HaakeDepartment of Clinical Sciences, Division of Oncology, Lund University, 221 85 Lund, Sweden.
Emma NilssonDepartment of Clinical Sciences, Division of Oncology, Lund University, 221 85 Lund, Sweden.
Helga TryggvadottirDepartment of Clinical Sciences, Division of Oncology, Lund University, 221 85 Lund, Sweden.
Linn NilssonDepartment of Clinical Sciences, Division of Oncology, Lund University, 221 85 Lund, Sweden.
Björn NodinDepartment of Clinical Sciences, Division of Oncology, Lund University, 221 85 Lund, Sweden.
Karin JirströmDepartment of Clinical Sciences, Division of Oncology, Lund University, 221 85 Lund, Sweden.
Karolin IsakssonDepartment of Clinical Sciences, Division of Surgery, Lund University, 221 85 Lund, Sweden.
Helena JernströmDepartment of Clinical Sciences, Division of Oncology, Lund University, 221 85 Lund, Sweden.ORCID 0000-0002-2301-5147
Lund University · SE

Funding

Gorthonstiftelsen 2022-2820Swedish Cancer Society CAN 20 0763
6 · The paper itself

Abstract

Previous research has indicated an association between the presence of the vitamin D receptor (VDR) in breast cancer tissue and a favorable prognosis. This study aimed to further evaluate the prognostic potential of VDR located in the nuclear membrane or nucleus (liganded). The VDR protein levels were analyzed using immunohistochemistry in tumor samples from 878 breast cancer patients from Lund, Sweden, included in the Breast Cancer and Blood Study (BCBlood) from October 2002 to June 2012. The follow-up for breast cancer events and overall survival was recorded until 30 June 2019. Univariable and multivariable survival analyses were conducted, both with complete case data and with missing data imputed using multiple imputation by chained equations (MICE). Tumor-specific positive nuclear membrane VDR

Indexed as

Breast NeoplasmsBreastCohort StudiesFemaleHumansPrognosisReceptors, CalcitriolReceptors, Calcitriolbreast cancerbreast cancer free intervaloverall survivalprognosisvitamin D receptor

Identifiers

PMID38612962
PMCPMC11013402
OpenAlexW4393141972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.