Evidence map›Paper›PMID 38612926›Full record

ArticleInternational journal of molecular sciences2024

Tumor and Peritoneum-Associated Macrophage Gene Signature as a Novel Molecular Biomarker in Gastric Cancer.

Kevin M Sullivan, Haiqing Li, Annie Yang, Zhifang Zhang, Ruben R Munoz, Kelly M Mahuron, Yate-Ching Yuan, Isaac Benjamin Paz, Daniel Von Hoff, Haiyong Han and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Spatial transcriptomics reveals prognostically LYZCancer immunology, immunotherapy : CII · 2025
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Kevin M SullivanDepartment of Surgery, City of Hope National Medical Center, Duarte, CA 91010, USA.ORCID 0000-0001-7455-2308
Haiqing LiIntegrative Genome Core, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA.
Annie YangDepartment of Surgery, City of Hope National Medical Center, Duarte, CA 91010, USA.
Zhifang ZhangDepartment of Surgery, City of Hope National Medical Center, Duarte, CA 91010, USA.
Ruben R MunozMolecular Medicine Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Kelly M MahuronDepartment of Surgery, City of Hope National Medical Center, Duarte, CA 91010, USA.
Yate-Ching YuanIntegrative Genome Core, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA.ORCID 0000-0002-3698-9784
Isaac Benjamin PazDepartment of Surgery, City of Hope National Medical Center, Duarte, CA 91010, USA.
Daniel Von HoffMolecular Medicine Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.ORCID 0000-0003-4723-7681
Haiyong HanMolecular Medicine Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
Yuman FongDepartment of Surgery, City of Hope National Medical Center, Duarte, CA 91010, USA.
Yanghee WooDepartment of Surgery, City of Hope National Medical Center, Duarte, CA 91010, USA.
City Of Hope National Medical Center · USTranslational Genomics Research Institute · US

Funding

United States Department of Defense W81XWH-19-1-0225
6 · The paper itself

Abstract

A spectrum of immune states resulting from tumor resident macrophages and T-lymphocytes in the solid tumor microenvironment correlates with patient outcomes. We hypothesized that in gastric cancer (GC), macrophages in a polarized immunosuppressive transcriptional state would be prognostic of poor survival. We derived transcriptomic signatures for M2 (M2

Indexed as

Stomach NeoplasmsBiomarkersFibrinogenHumansMacrophagesMacrophages, PeritonealPeritoneumTumor MicroenvironmentBiomarkersFGL2 protein, humanFibrinogenbiomarkergastric cancerliquid biopsymacrophageperitoneal metastases

Identifiers

PMID38612926
PMCPMC11012629
OpenAlexW4394579485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.