Evidence map›Paper›PMID 38612916›Full record

ArticleInternational journal of molecular sciences2024

The Catalytic Activity of Human REV1 on Undamaged and Damaged DNA.

Anastasia D Stolyarenko, Anna A Novikova, Evgeniy S Shilkin, Valentin A Poltorachenko, Alena V Makarova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anastasia D StolyarenkoNational Research Center "Kurchatov Institute", 123182 Moscow, Russia.ORCID 0000-0002-6624-1187
Anna A NovikovaNational Research Center "Kurchatov Institute", 123182 Moscow, Russia.
Evgeniy S ShilkinNational Research Center "Kurchatov Institute", 123182 Moscow, Russia.
Valentin A PoltorachenkoNational Research Center "Kurchatov Institute", 123182 Moscow, Russia.
Alena V MakarovaNational Research Center "Kurchatov Institute", 123182 Moscow, Russia.ORCID 0000-0002-6513-892X
Kurchatov Institute · RU

Funding

Russian Science Foundation 22-24-20155
6 · The paper itself

Abstract

Eukaryotic REV1 serves as a scaffold protein for the coordination of DNA polymerases during DNA translesion synthesis. Besides this structural role, REV1 is a Y-family DNA polymerase with its own distributive deoxycytidyl transferase activity. However, data about the accuracy and efficiency of DNA synthesis by REV1 in the literature are contrasting. Here, we expressed and purified the full-length human REV1 from

Indexed as

AdenineCisplatinDNA DamageDNA-Directed DNA PolymeraseDNA ReplicationHumansNucleotidyltransferasesSaccharomyces cerevisiaeY-Family DNA PolymerasesAdenineCisplatinDNA-Directed DNA PolymeraseNucleotidyltransferasesREV1 protein, humanY-Family DNA PolymerasesAP sitecisplatin intrastrand crosslinkDNA polymeraseHoogsteen interactionsREV1translesion DNA synthesis

Identifiers

PMID38612916
PMCPMC11012841
OpenAlexW4394567728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.