Evidence map›Paper›PMID 38612837›Full record

ArticleInternational journal of molecular sciences2024

Prevalence of Selected Polymorphisms of Il7R, CD226, CAPSL, and CLEC16A Genes in Children and Adolescents with Autoimmune Thyroid Diseases.

Hanna Borysewicz-Sańczyk, Natalia Wawrusiewicz-Kurylonek, Joanna Gościk, Beata Sawicka, Filip Bossowski, Domenico Corica, Tommaso Aversa, Małgorzata Waśniewska, Artur Bossowski

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Hanna Borysewicz-SańczykDepartment of Pediatrics, Endocrinology, Diabetology with Cardiology Divisions, Medical University of Bialystok, J. Waszyngtona 17, 15-274 Bialystok, Poland.
Natalia Wawrusiewicz-KurylonekDepartment of Clinical Genetics, Medical University of Bialystok, J. Waszyngtona 13, 15-089 Bialystok, Poland.ORCID 0000-0002-1087-8154
Joanna GościkFaculty of Computer Science, Bialystok University of Technology, Wiejska 45A, 15-351 Bialystok, Poland.
Beata SawickaDepartment of Pediatrics, Endocrinology, Diabetology with Cardiology Divisions, Medical University of Bialystok, J. Waszyngtona 17, 15-274 Bialystok, Poland.
Filip BossowskiDepartment of Pediatrics, Endocrinology, Diabetology with Cardiology Divisions, Medical University of Bialystok, J. Waszyngtona 17, 15-274 Bialystok, Poland.ORCID 0000-0002-0229-4597
Domenico CoricaUnit of Pediatrics, Department of Human Pathology of Adulthood and Childhood, University of Messina, Via Consolare Valeria Cap, 98125 Messina, Italy.
Tommaso AversaUnit of Pediatrics, Department of Human Pathology of Adulthood and Childhood, University of Messina, Via Consolare Valeria Cap, 98125 Messina, Italy.ORCID 0000-0002-1754-6822
Małgorzata WaśniewskaUnit of Pediatrics, Department of Human Pathology of Adulthood and Childhood, University of Messina, Via Consolare Valeria Cap, 98125 Messina, Italy.ORCID 0000-0002-8299-2677
Artur BossowskiDepartment of Pediatrics, Endocrinology, Diabetology with Cardiology Divisions, Medical University of Bialystok, J. Waszyngtona 17, 15-274 Bialystok, Poland.ORCID 0000-0002-6316-5342
Medical University of Białystok · PLUniversity of Messina · ITBialystok University of Technology · PL

Funding

Medical University of Białystok B.SUB.23.340
6 · The paper itself

Abstract

Hashimoto's thyroiditis (HT) and Graves' disease (GD) are common autoimmune endocrine disorders in children. Studies indicate that apart from environmental factors, genetic background significantly contributes to the development of these diseases. This study aimed to assess the prevalence of selected single-nucleotide polymorphisms (SNPs) of Il7R, CD226, CAPSL, and CLEC16A genes in children with autoimmune thyroid diseases. We analyzed SNPs at the locus rs3194051, rs6897932 of IL7R, rs763361 of CD226, rs1010601 of CAPSL, and rs725613 of CLEC16A gene in 56 HT patients, 124 GD patients, and 156 healthy children. We observed significant differences in alleles IL7R (rs6897932) between HT males and the control group (C > T,

Indexed as

Autoimmune DiseasesGraves DiseaseHashimoto DiseaseAdolescentAllelesChildFemaleHumansLectins, C-TypeMaleMonosaccharide Transport ProteinsPolymorphism, Single NucleotidePrevalenceReceptors, Interleukin-7CLEC16A protein, humanLectins, C-TypeMonosaccharide Transport ProteinsReceptors, Interleukin-7autoimmune thyroid diseases (AITDs)CAPSLCD226childrenCLEC16Agenetic susceptibilityGraves’ disease (GD)Hashimoto’s thyroiditis (HT)Il7Rsingle-nucleotide polymorphism (SNP)

Identifiers

PMID38612837
PMCPMC11012896
OpenAlexW4393950447

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.