Evidence map›Paper›PMID 38612823›Full record

ArticleInternational journal of molecular sciences2024

Modeling Dynamics of Human Gut Microbiota Derived from Gluten Metabolism: Obtention, Maintenance and Characterization of Complex Microbial Communities.

Yaiza Carnicero-Mayo, Luis E Sáenz de Miera, Miguel Ángel Ferrero, Nicolás Navasa, Javier Casqueiro

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Special Issue: "Gut Microbiota and Nutrition in Human Health".International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yaiza Carnicero-MayoÁrea de Microbiología, Facultad de Ciencias Biológicas y Ambientales, Universidad de León, 24007 León, Spain.ORCID 0000-0002-1539-1249
Luis E Sáenz de MieraÁrea de Genética, Facultad de Ciencias Biológicas y Ambientales, Universidad de León, 24007 León, Spain.ORCID 0000-0003-1871-7379
Miguel Ángel FerreroÁrea de Bioquímica y Biología Molecular, Facultad de Veterinaria, Universidad de León, 24007 León, Spain.
Nicolás NavasaÁrea de Bioquímica y Biología Molecular, Facultad de Veterinaria, Universidad de León, 24007 León, Spain.ORCID 0000-0001-9393-9348
Javier CasqueiroÁrea de Microbiología, Facultad de Ciencias Biológicas y Ambientales, Universidad de León, 24007 León, Spain.ORCID 0000-0001-9046-2708
Universidad de León · ES

Funding

Junta de Castilla y León LE015P20Junta de Castilla y León Orden 12 de diciembre, 2019Ministerio de Ciencia e Innovación PID2020-119044GB-I00
6 · The paper itself

Abstract

Western diets are rich in gluten-containing products, which are frequently poorly digested. The human large intestine harbors microorganisms able to metabolize undigested gluten fragments that have escaped digestion by human enzymatic activities. The aim of this work was obtaining and culturing complex human gut microbial communities derived from gluten metabolism to model the dynamics of healthy human large intestine microbiota associated with different gluten forms. For this purpose, stool samples from six healthy volunteers were inoculated in media containing predigested gluten or predigested gluten plus non-digested gluten. Passages were carried out every 24 h for 15 days in the same medium and community composition along time was studied via V3-V4 16S rDNA sequencing. Diverse microbial communities were successfully obtained. Moreover, communities were shown to be maintained in culture with stable composition for 14 days. Under non-digested gluten presence, communities were enriched in members of

Indexed as

ActinobacteriaGastrointestinal MicrobiomeMicrobiotaBacillotaEubacterialesGlutensHumansGlutensglutengluten metabolismgut microbiotain vitro digestionmicrobial communities

Identifiers

PMID38612823
PMCPMC11012253
OpenAlexW4393935556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.