Evidence map›Paper›PMID 38612608›Full record

ReviewInternational journal of molecular sciences2024

Research Progress on Bioactive Factors against Skin Aging.

Xin He, Xinyu Gao, Yifan Guo, Weidong Xie

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07516756 (Impact of Oral Supplementation of Specific Bioactive Collagen Peptides on Human Skin Physiology), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
25.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07516756 nacompletednot on this map

Impact of Oral Supplementation of Specific Bioactive Collagen Peptides on Human Skin Physiology: A Randomized, Double-Blind, Placebo-Controlled Trial

TypeinterventionalSponsorCollagen Research InstituteRan2024 to 2024Enrolled66ConditionsAge-related Changes in Skin Appearance and PhysiologyArmsPlacebo, Specific Collagen Peptides
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 47 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Valorization ofPlants (Basel, Switzerland) · 2026
    Article
  10. Review
  11. Seed Oil ofInternational journal of molecular sciences · 2026
    Article
  12. Anti-Photoaging Effects of a Standardized Hot Water Extract ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  13. Article
  14. Evaluation ofMolecules (Basel, Switzerland) · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Gels (Basel, Switzerland) · 2025
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xin HeState Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
Xinyu GaoState Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
Yifan GuoState Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
Weidong XieState Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.ORCID 0000-0001-5561-7663
University Town of Shenzhen · CN

Funding

Shenzhen Science and Technology Program RCJC20200714114433069 and JCYJ20200109142818589
6 · The paper itself

Abstract

The relentless pursuit of effective strategies against skin aging has led to significant interest in the role of bioactive factors, particularly secondary metabolites from natural sources. The purpose of this study is to meticulously explore and summarize the recent advancements in understanding and utilization of bioactive factors against skin aging, with a focus on their sources, mechanisms of action, and therapeutic potential. Skin, the largest organ of the body, directly interacts with the external environment, making it susceptible to aging influenced by factors such as UV radiation, pollution, and oxidative stress. Among various interventions, bioactive factors, including peptides, amino acids, and secondary metabolites, have shown promising anti-aging effects by modulating the biological pathways associated with skin integrity and youthfulness. This article provides a comprehensive overview of these bioactive compounds, emphasizing collagen peptides, antioxidants, and herbal extracts, and discusses their effectiveness in promoting collagen synthesis, enhancing skin barrier function, and mitigating the visible signs of aging. By presenting a synthesis of the current research, this study aims to highlight the therapeutic potential of these bioactive factors in developing innovative anti-aging skin care solutions, thereby contributing to the broader field of dermatological research and offering new perspectives for future studies. Our findings underscore the importance of the continued exploration of bioactive compounds for their potential to revolutionize anti-aging skin care and improve skin health and aesthetics.

Indexed as

Skin AgingAmino AcidsCollagenPeptidesAmino AcidsCollagenPeptidesbiological activity factorcollagenenzymeoxidative stresspolypeptideskin aging

Identifiers

PMID38612608
PMCPMC11011925
OpenAlexW4393254343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.