Evidence map›Paper›PMID 38612601›Full record

ReviewInternational journal of molecular sciences2024

Exploring Skin Wound Healing Models and the Impact of Natural Lipids on the Healing Process.

Vivek Choudhary, Mrunal Choudhary, Wendy B Bollag

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
24.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Ameliorative effects ofMolecular medicine reports · 2026
    Article
  4. Review
  5. Review
  6. Callus Induction inPlants (Basel, Switzerland) · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Food science & nutrition · 2026
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vivek ChoudharyDepartment of Physiology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-3664-5025
Mrunal ChoudharyDepartment of Physiology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Wendy B BollagDepartment of Physiology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0003-3146-162X
Augusta University · US

Funding

Epidermal Aquaporin-3 in PsoriasisI01CX001357 · VA · CHARLIE NORWOOD VA MEDICAL CENTER · PI BOLLAG, WENDY B · 2016 to 2020
–
BLRD Research Career Scientist Award ApplicationIK6BX005691 · VA · CHARLIE NORWOOD VA MEDICAL CENTER · PI BOLLAG, WENDY B · 2021 to 2025
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BLRD VA IK6 BX005691CSRD VA I01 CX001357
6 · The paper itself

Abstract

Cutaneous wound healing is a complex biological process involving a series of well-coordinated events aimed at restoring skin integrity and function. Various experimental models have been developed to study the mechanisms underlying skin wound repair and to evaluate potential therapeutic interventions. This review explores the diverse array of skin wound healing models utilized in research, ranging from rodent excisional wounds to advanced tissue engineering constructs and microfluidic platforms. More importantly, the influence of lipids on the wound healing process is examined, emphasizing their role in enhancing barrier function restoration, modulating inflammation, promoting cell proliferation, and promoting remodeling. Lipids, such as phospholipids, sphingolipids, and ceramides, play crucial roles in membrane structure, cell signaling, and tissue repair. Understanding the interplay between lipids and the wound microenvironment provides valuable insights into the development of novel therapeutic strategies for promoting efficient wound healing and tissue regeneration. This review highlights the significance of investigating skin wound healing models and elucidating the intricate involvement of lipids in the healing process, offering potential avenues for improving clinical outcomes in wound management.

Indexed as

CeramidesInflammationCell ProliferationHumansMicrofluidicsPhospholipidsCeramidesPhospholipidscutaneous wound healingepidermal regenerationinflammationin vivo modelskeratinocyteslipidphosphatidylglycerolskin

Identifiers

PMID38612601
PMCPMC11011291
OpenAlexW4393255425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.