Evidence map›Paper›PMID 38612547›Full record

ArticleInternational journal of molecular sciences2024

Impact of Protein Nanoparticle Shape on the Immunogenicity of Antimicrobial Glycoconjugate Vaccines.

Marta Dolce, Daniela Proietti, Silvia Principato, Fabiola Giusti, Giusy Manuela Adamo, Sara Favaron, Elia Ferri, Immaculada Margarit, Maria Rosaria Romano, Maria Scarselli and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Marta DolceDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-8936-1552
Daniela ProiettiGSK, 53100 Siena, Italy.
Silvia PrincipatoGSK, 53100 Siena, Italy.
Fabiola GiustiGSK, 53100 Siena, Italy.
Giusy Manuela AdamoGSK, 53100 Siena, Italy.
Sara FavaronGSK, 53100 Siena, Italy.ORCID 0009-0008-9260-3752
Elia FerriGSK, 53100 Siena, Italy.
Immaculada MargaritGSK, 53100 Siena, Italy.
Maria Rosaria RomanoGSK, 53100 Siena, Italy.
Maria ScarselliGSK, 53100 Siena, Italy.
Filippo CarboniGSK, 53100 Siena, Italy.ORCID 0009-0001-6792-3147
Politecnico di Milano · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein self-assembling nanoparticles (NPs) can be used as carriers for antigen delivery to increase vaccine immunogenicity. NPs mimic the majority of invading pathogens, inducing a robust adaptive immune response and long-lasting protective immunity. In this context, we investigated the potential of NPs of different sizes and shapes-ring-, rod-like, and spherical particles-as carriers for bacterial oligosaccharides by evaluating in murine models the role of these parameters on the immune response. Oligosaccharides from

Indexed as

Anti-Infective AgentsNanoparticlesAnimalsFerritinsGlycoconjugatesMiceOligosaccharidesAnti-Infective AgentsFerritinsGlycoconjugatesOligosaccharidesantimicrobial vaccinesglycoconjugatesprotein nanoparticlesvaccines

Identifiers

PMID38612547
PMCPMC11011275
OpenAlexW4393218731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.