Evidence map›Paper›PMID 38612491›Full record

ArticleInternational journal of molecular sciences2024

Unveiling the Genetic Mechanism of Meat Color in Pigs through GWAS, Multi-Tissue, and Single-Cell Transcriptome Signatures Exploration.

Cheng Liu, Zitao Chen, Zhe Zhang, Zhen Wang, Xiaoling Guo, Yuchun Pan, Qishan Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Application of GWAS and mGWAS in Livestock and Poultry Breeding.Animals : an open access journal from MDPI · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cheng LiuDepartment of Animal Science, College of Animal Science, Zhejiang University, 866# Yuhangtang Road, Hangzhou 310058, China.
Zitao ChenDepartment of Animal Science, College of Animal Science, Zhejiang University, 866# Yuhangtang Road, Hangzhou 310058, China.ORCID 0000-0001-6213-0810
Zhe ZhangDepartment of Animal Science, College of Animal Science, Zhejiang University, 866# Yuhangtang Road, Hangzhou 310058, China.
Zhen WangDepartment of Animal Science, College of Animal Science, Zhejiang University, 866# Yuhangtang Road, Hangzhou 310058, China.
Xiaoling GuoDepartment of Animal Science, College of Animal Science, Zhejiang University, 866# Yuhangtang Road, Hangzhou 310058, China.
Yuchun PanDepartment of Animal Science, College of Animal Science, Zhejiang University, 866# Yuhangtang Road, Hangzhou 310058, China.
Qishan WangDepartment of Animal Science, College of Animal Science, Zhejiang University, 866# Yuhangtang Road, Hangzhou 310058, China.ORCID 0000-0002-6475-0009
Zhejiang University · CN

Funding

National Key Research and Development Program of China 2021YFD1200802National Natural Science Foundation of China 32272833National Natural Science Foundation of China U21A20249Zhejiang Science and Technology Major Program on Agricultural New Variety Breeding 2021C02068-1
6 · The paper itself

Abstract

Meat color traits directly influence consumer acceptability and purchasing decisions. Nevertheless, there is a paucity of comprehensive investigation into the genetic mechanisms underlying meat color traits in pigs. Utilizing genome-wide association studies (GWAS) on five meat color traits and the detection of selection signatures in pig breeds exhibiting distinct meat color characteristics, we identified a promising candidate SNP, 6_69103754, exhibiting varying allele frequencies among pigs with different meat color characteristics. This SNP has the potential to affect the redness and chroma index values of pork. Moreover, transcriptome-wide association studies (TWAS) analysis revealed the expression of candidate genes associated with meat color traits in specific tissues. Notably, the largest number of candidate genes were observed from transcripts derived from adipose, liver, lung, spleen tissues, and macrophage cell type, indicating their crucial role in meat color development. Several shared genes associated with redness, yellowness, and chroma indices traits were identified, including

Indexed as

Genome-Wide Association StudyTranscriptomeAdipose TissueAdiposityAnimalsMeatSwineGWASmeat qualitysingle-cell enrichmentTWAS

Identifiers

PMID38612491
PMCPMC11012088
OpenAlexW4393189901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.