Evidence map›Paper›PMID 38612488›Full record

ReviewInternational journal of molecular sciences2024

Assessment and Risk Prediction of Chronic Kidney Disease and Kidney Fibrosis Using Non-Invasive Biomarkers.

Harald Rupprecht, Lorenzo Catanese, Kerstin Amann, Felicitas E Hengel, Tobias B Huber, Agnieszka Latosinska, Maja T Lindenmeyer, Harald Mischak, Justyna Siwy, Ralph Wendt and 1 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. [Histology and more-modern nephropathology].Innere Medizin (Heidelberg, Germany) · 2026
    Review
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Harald RupprechtDepartment of Nephrology, Angiology and Rheumatology, Klinikum Bayreuth GmbH, 95445 Bayreuth, Germany.
Lorenzo CataneseDepartment of Nephrology, Angiology and Rheumatology, Klinikum Bayreuth GmbH, 95445 Bayreuth, Germany.ORCID 0000-0002-9933-8364
Kerstin AmannDepartment of Nephropathology, Institute of Pathology, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Felicitas E HengelIII Department of Medicine, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.ORCID 0000-0003-4899-414X
Tobias B HuberIII Department of Medicine, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Agnieszka LatosinskaMosaiques Diagnostics GmbH, 30659 Hannover, Germany.
Maja T LindenmeyerIII Department of Medicine, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Harald MischakMosaiques Diagnostics GmbH, 30659 Hannover, Germany.ORCID 0000-0003-0323-0306
Justyna SiwyMosaiques Diagnostics GmbH, 30659 Hannover, Germany.ORCID 0000-0003-1407-2534
Ralph WendtDepartment of Nephrology, Hospital St. Georg, 04129 Leipzig, Germany.ORCID 0000-0003-1600-6581
Joachim BeigeDepartment of Nephrology, Hospital St. Georg, 04129 Leipzig, Germany.

Funding

European Union 101072828Federal Ministry of Education and Research 01EK2105
6 · The paper itself

Abstract

Effective management of chronic kidney disease (CKD), a major health problem worldwide, requires accurate and timely diagnosis, prognosis of progression, assessment of therapeutic efficacy, and, ideally, prediction of drug response. Multiple biomarkers and algorithms for evaluating specific aspects of CKD have been proposed in the literature, many of which are based on a small number of samples. Based on the evidence presented in relevant studies, a comprehensive overview of the different biomarkers applicable for clinical implementation is lacking. This review aims to compile information on the non-invasive diagnostic, prognostic, and predictive biomarkers currently available for the management of CKD and provide guidance on the application of these biomarkers. We specifically focus on biomarkers that have demonstrated added value in prospective studies or those based on prospectively collected samples including at least 100 subjects. Published data demonstrate that several valid non-invasive biomarkers of potential value in the management of CKD are currently available.

Indexed as

Renal Insufficiency, ChronicBiomarkersFibrosisHumansKidneyProspective StudiesBiomarkersbiomarkerfibrosiskidney diseaseprogressionresponse prediction

Identifiers

PMID38612488
PMCPMC11011737

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.