Evidence map›Paper›PMID 38612449›Full record

ArticleInternational journal of molecular sciences2024

The Role of Heat-Induced Stress Granules in the Blood-Testis Barrier of Mice.

Zhifeng Zhao, Yuqing Cai, Xinyi Lin, Ning Liu, Yinghe Qin, Yingjie Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhifeng ZhaoCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-1145-1638
Yuqing CaiCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Xinyi LinCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Ning LiuCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-7484-0534
Yinghe QinCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Yingjie WuCollege of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
China Agricultural University · CN

Funding

Earmarked Fund for Modern Agro-Industry Technology Research System CARS-43STI 2030-Major Projects 2023ZD0407502
6 · The paper itself

Abstract

Stress granules (SGs) are membraneless ribonucleoprotein (RNP)-based cellular foci formed in response to stress, facilitating cell survival by protecting against damage. Mammalian spermatogenesis should be maintained below body temperature for proper development, indicating its vulnerability to heat stress (HS). In this study, biotin tracer permeability assays showed that the inhibition of heat-induced SG assembly in the testis by 4-8 mg/kg cycloheximide significantly increased the percentage of seminiferous tubules with a damaged blood-testis barrier (BTB). Western blot results additionally revealed that the suppression of heat-induced SG assembly in Sertoli cell line, TM4 cells, by RNA inference of

Indexed as

Blood-Testis BarrierDNA HelicasesAnimalsbeta CateninClaudinsMaleMammalsMicePoly-ADP-Ribose Binding ProteinsRNARNA HelicasesRNA Recognition Motif ProteinsStress Granulesbeta CateninClaudinsDNA HelicasesPoly-ADP-Ribose Binding ProteinsRNARNA HelicasesRNA Recognition Motif Proteinsblood–testis barrierheat stressstress granuleUBAP2

Identifiers

PMID38612449
PMCPMC11011666
OpenAlexW4393142768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.