Evidence map›Paper›PMID 38612418›Full record

ArticleInternational journal of molecular sciences2024

Six-Gene Signature for Differential Diagnosis and Therapeutic Decisions in Non-Small-Cell Lung Cancer-A Validation Study.

Radoslaw Charkiewicz, Anetta Sulewska, Piotr Karabowicz, Grzegorz Lapuc, Alicja Charkiewicz, Marcin Kraska, Joanna Pancewicz, Malgorzata Lukasik, Miroslaw Kozlowski, Rafal Stec and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Radoslaw CharkiewiczCenter of Experimental Medicine, Medical University of Bialystok, 15-369 Bialystok, Poland.ORCID 0000-0001-7864-6483
Anetta SulewskaDepartment of Clinical Molecular Biology, Medical University of Bialystok, 15-269 Bialystok, Poland.ORCID 0000-0001-7070-8491
Piotr KarabowiczBiobank, Medical University of Bialystok, 15-269 Bialystok, Poland.
Grzegorz LapucDepartment of Thoracic Surgery, Medical University of Bialystok, 15-269 Bialystok, Poland.
Alicja CharkiewiczDepartment of Analysis and Bioanalysis of Medicines, Medical University of Bialystok, 15-089 Bialystok, Poland.
Marcin KraskaDepartment of Clinical Molecular Biology, Medical University of Bialystok, 15-269 Bialystok, Poland.
Joanna PancewiczDepartment of Histology and Embryology, Medical University of Bialystok, 15-269 Bialystok, Poland.ORCID 0000-0003-3194-9107
Malgorzata LukasikDepartment of Histology and Embryology, Medical University of Bialystok, 15-269 Bialystok, Poland.
Miroslaw KozlowskiDepartment of Thoracic Surgery, Medical University of Bialystok, 15-269 Bialystok, Poland.
Rafal StecDepartment of Oncology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Dominika ZiembickaDepartment of Public Health, Medical University of Bialystok, 15-295 Bialystok, Poland.
Weronika PiszczDepartment of Clinical Molecular Biology, Medical University of Bialystok, 15-269 Bialystok, Poland.
Wojciech MiltykDepartment of Analysis and Bioanalysis of Medicines, Medical University of Bialystok, 15-089 Bialystok, Poland.ORCID 0000-0001-5150-6093
Wieslawa NiklinskaDepartment of Histology and Embryology, Medical University of Bialystok, 15-269 Bialystok, Poland.
Medical University of Białystok · PLMedical University of Warsaw · PL

Funding

National Centre for Research and Development STRATEGMED2/266484/2/NCBR/2015
6 · The paper itself

Abstract

Non-small-cell lung cancer (NSCLC) poses a challenge due to its heterogeneity, necessitating precise histopathological subtyping and prognostication for optimal treatment decision-making. Molecular markers emerge as a potential solution, overcoming the limitations of conventional methods and supporting the diagnostic-therapeutic interventions. In this study, we validated the expression of six genes (

Indexed as

AdenocarcinomaCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellLung NeoplasmsSmall Cell Lung CarcinomaDiagnosis, DifferentialHumansADCgene expressionNSCLC subtypingpersonalized medicineprognosisqPCRSCCvalidation study

Identifiers

PMID38612418
PMCPMC11011743
OpenAlexW4393158508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.