Evidence map›Paper›PMID 38612414›Full record

ReviewInternational journal of molecular sciences2024

Emerging Molecular and Synaptic Targets for the Management of Chronic Pain Caused by Systemic Lupus Erythematosus.

Han-Rong Weng

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Han-Rong WengDepartment of Basic Sciences, California Northstate University College of Medicine, Elk Grove, CA 95757, USA.
California Northstate University · US

Funding

Targeting GPR109A for the treatment of pain in systemic lupus erythematosusR01NS107569 · NINDS · UNIVERSITY OF GEORGIA · PI WENG, HAN-RONG · 2018 to 2022
$1.4M
NINDS NIH HHS R01 NS107569
6 · The paper itself

Abstract

Patients with systemic lupus erythematosus (SLE) frequently experience chronic pain due to the limited effectiveness and safety profiles of current analgesics. Understanding the molecular and synaptic mechanisms underlying abnormal neuronal activation along the pain signaling pathway is essential for developing new analgesics to address SLE-induced chronic pain. Recent studies, including those conducted by our team and others using the SLE animal model (

Indexed as

Chronic PainLupus Erythematosus, SystemicAMP-Activated Protein KinasesAnalgesicsAnimalsGlutamic AcidHumansInterleukin-18Interleukin-1betaMiceMice, Inbred MRL lprAMP-Activated Protein KinasesAnalgesicsGlutamic AcidInterleukin-18Interleukin-1betacytokinesDRGHCA2neuroinflammationnociceptionrheumatological

Identifiers

PMID38612414
PMCPMC11011483
OpenAlexW4393162554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.