Evidence map›Paper›PMID 38611742›Full record

ReviewMolecules (Basel, Switzerland)2024

Nanomaterial Delivery Vehicles for the Development of Neoantigen Tumor Vaccines for Personalized Treatment.

Xiaoyu Huang, Xiaolong Zhu, Huan Yang, Qinyi Li, Lizhi Gai, Xinbing Sui, Hua Lu, Jiao Feng

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiaoyu HuangSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Xiaolong ZhuSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Huan YangSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Qinyi LiSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Lizhi GaiCollege of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, and Key Laboratory of Organosilicon Material Technology of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Xinbing SuiSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Hua LuCollege of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, and Key Laboratory of Organosilicon Material Technology of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China.
Jiao FengSchool of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Hangzhou Normal University · CN

Funding

National Natural Science Foundation of China No. 82202847Zhejiang Provincial Natural Science Foundation of China LQ21H160038
6 · The paper itself

Abstract

Tumor vaccines have been considered a promising therapeutic approach for treating cancer in recent years. With the development of sequencing technologies, tumor vaccines based on neoantigens or genomes specifically expressed in tumor cells, mainly in the form of peptides, nucleic acids, and dendritic cells, are beginning to receive widespread attention. Therefore, in this review, we have introduced different forms of neoantigen vaccines and discussed the development of these vaccines in treating cancer. Furthermore, neoantigen vaccines are influenced by factors such as antigen stability, weak immunogenicity, and biosafety in addition to sequencing technology. Hence, the biological nanomaterials, polymeric nanomaterials, inorganic nanomaterials, etc., used as vaccine carriers are principally summarized here, which may contribute to the design of neoantigen vaccines for improved stability and better efficacy.

Indexed as

Cancer VaccinesNanostructuresNeoplasmsNucleic AcidsHumansPrecision MedicineCancer VaccinesNucleic Acidsnanomaterialsneoantigenpersonalized treatmenttumor vaccinesvaccine delivery

Identifiers

PMID38611742
PMCPMC11012694
OpenAlexW4393158668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.