Evidence map›Paper›PMID 38611714›Full record

ArticleMolecules (Basel, Switzerland)2024

Tetramethylpyrazine Antagonizes the Subchronic Cadmium Exposure-Induced Oxidative Damage in Mouse Livers via the Nrf2/HO-1 Pathway.

Xue Hu, Siqi Zhao, Ziming Guo, Yiling Zhu, Shuai Zhang, Danqin Li, Gang Shu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Xue HuCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Siqi ZhaoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Ziming GuoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Yiling ZhuCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Shuai ZhangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Danqin LiCollege of Veterinary Medicine, Kansas State University, 1700 Denison Ave., Manhattan, KS 66502, USA.
Gang ShuCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-0610-9635
Sichuan Agricultural University · CNKansas State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic oxidative stress is an important mechanism of Cd-induced hepatotoxicity, and it is ameliorated by TMP. However, this underlying mechanism remains to be elucidated. To investigate the mechanism of the protective effect of TMP on liver injuries in mice induced by subchronic cadmium exposure, 60 healthy male ICR mice were randomly divided into five groups of 12 mice each, namely, control (CON), Cd (2 mg/kg of CdCl

Indexed as

CadmiumNF-E2-Related Factor 2PyrazinesAnimalsLiverMaleMiceMice, Inbred ICROxidative StressRNA, MessengerCadmiumNF-E2-Related Factor 2PyrazinesRNA, Messengertetramethylpyrazinecadmium (Cd)liverNrf2 pathwayoxidative stresstetramethylpyrazine

Identifiers

PMID38611714
PMCPMC11013177
OpenAlexW4393143281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.