Evidence map›Paper›PMID 38611689›Full record

ArticleDiagnostics (Basel, Switzerland)2024

The Clinical Impact of the Pulmonary Embolism Severity Index on the Length of Hospital Stay of Patients with Pulmonary Embolism: A Randomized Controlled Trial.

Marco Paolo Donadini, Nicola Mumoli, Patrizia Fenu, Fulvio Pomero, Roberta Re, Gerardo Palmiero, Laura Spadafora, Valeria Mazzi, Alessandra Grittini, Lorenza Bertù and 4 more

Registry-linked trialAbstract read
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In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03002467 (Impact Analysis of Prognostic Stratification for Pulmonary Embolism), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03002467 naterminatednot on this map

Impact Analysis of Prognostic Stratification for Pulmonary Embolism: A Randomized Controlled Trial

TypeinterventionalSponsorUniversità degli Studi dell'InsubriaRan2016 to 2019Enrolled125ConditionsPulmonary EmbolismArmsPESI score
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marco Paolo DonadiniThrombosis and Haemostasis Center, Ospedale di Circolo, ASST Sette Laghi, 21100 Varese, Italy.ORCID 0000-0001-5065-318X
Nicola MumoliDepartment of Internal Medicine, Magenta Hospital, 20013 Magenta, Italy.ORCID 0000-0001-7166-5630
Patrizia FenuPresidio Ospedaliero di Cecina, Azienda USL Toscana Nord Ovest, 57023 Cecina, Italy.
Fulvio PomeroInternal Medicine Unit, Michele e Pietro Ferrero Hospital, 12060 Verduno, Italy.ORCID 0000-0003-0991-2615
Roberta ReMedicina Interna, Ospedale S. Andrea, ASL Vercelli, 13100 Vercelli, Italy.
Gerardo PalmieroOspedale Versilia, Azienda USL Toscana Nord Ovest, 55049 Viareggio, Italy.ORCID 0000-0003-4219-5793
Laura SpadaforaInternal Medicine Unit, Michele e Pietro Ferrero Hospital, 12060 Verduno, Italy.
Valeria MazziPresidio Ospedaliero di Livorno, Azienda USL Toscana Nord Ovest, 57124 Livorno, Italy.
Alessandra GrittiniDepartment of Internal Medicine, Magenta Hospital, 20013 Magenta, Italy.
Lorenza BertùResearch Center on Thromboembolic Diseases and Antithrombotic Therapies, University of Insubria, 21100 Varese and 22100 Como, Italy.
Drahomir AujeskyDepartment of General Internal Medicine, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Francesco DentaliThrombosis and Haemostasis Center, Ospedale di Circolo, ASST Sette Laghi, 21100 Varese, Italy.
Walter AgenoThrombosis and Haemostasis Center, Ospedale di Circolo, ASST Sette Laghi, 21100 Varese, Italy.
Alessandro SquizzatoResearch Center on Thromboembolic Diseases and Antithrombotic Therapies, University of Insubria, 21100 Varese and 22100 Como, Italy.ORCID 0000-0001-5705-2897

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Pulmonary Embolism Severity Index (PESI) is an extensively validated prognostic score, but impact analyses of the PESI on management strategies, outcomes and health care costs are lacking. Our aim was to assess whether the adoption of the PESI for patients admitted to an internal medicine ward has the potential to safely reduce the length of hospital stay (LOS).

methodsWe carried out a multicenter randomized controlled trial, enrolling consecutive adult outpatients diagnosed with acute PE and admitted to an internal medicine ward. Within 48 h after diagnosis, the treating physicians were randomized, for every patient, to calculate and report the PESI in the clinical record form on top of the standard of care (experimental arm) or to continue routine clinical practice (standard of care). The ClinicalTrials.gov identifier is NCT03002467.

resultsThis study was prematurely stopped due to slow recruitment. A total of 118 patients were enrolled at six internal medicine units from 2016 to 2019. The treating physicians were randomized to the use of the PESI for 59 patients or to the standard of care for 59 patients. No difference in the median LOS was found between the experimental arm (8, IQR 6-12) and the standard-of-care arm (8, IQR 6-12) (

conclusionsThe formal calculation of the PESI in the patients already admitted to internal medicine units did not impact the length of hospital stay.

Indexed as

length of hospital staypulmonary embolismPulmonary Embolism Severity Index

Identifiers

PMID38611689
PMCPMC11011567

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.