Evidence map›Paper›PMID 38611284›Full record

ReviewFoods (Basel, Switzerland)2024

Phytochemicals Involved in Mitigating Silent Toxicity Induced by Heavy Metals.

Jessica Ceramella, Azzurra Chiara De Maio, Giovanna Basile, Anastasia Facente, Elisabetta Scali, Inmaculada Andreu, Maria Stefania Sinicropi, Domenico Iacopetta, Alessia Catalano

Open access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Sustainable Valorization ofMolecules (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Role ofAntioxidants (Basel, Switzerland) · 2024
    Article
  16. Foods (Basel, Switzerland) · 2024
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Jessica CeramellaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Cosenza, Italy.ORCID 0000-0002-1386-3601
Azzurra Chiara De MaioDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Cosenza, Italy.
Giovanna BasileDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Cosenza, Italy.
Anastasia FacenteDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Cosenza, Italy.
Elisabetta ScaliUnit of Dermatology, Spoke Hospital, Locri, 89044 Reggio Calabria, Italy.
Inmaculada AndreuDepartamento de Química, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain.ORCID 0000-0003-3409-9443
Maria Stefania SinicropiDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Cosenza, Italy.ORCID 0000-0003-2435-8931
Domenico IacopettaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Cosenza, Italy.ORCID 0000-0001-5179-7118
Alessia CatalanoDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70126 Bari, Italy.ORCID 0000-0002-7420-4706
University of Calabria · ITHospital Universitari i Politècnic La Fe · ESMagna Graecia University · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heavy metals (HMs) are natural elements present in the Earth's crust, characterised by a high atomic mass and a density more than five times higher than water. Despite their origin from natural sources, extensive usage and processing of raw materials and their presence as silent poisons in our daily products and diets have drastically altered their biochemical balance, making them a threat to the environment and human health. Particularly, the food chain polluted with toxic metals represents a crucial route of human exposure. Therefore, the impact of HMs on human health has become a matter of concern because of the severe chronic effects induced by their excessive levels in the human body. Chelation therapy is an approved valid treatment for HM poisoning; however, despite the efficacy demonstrated by chelating agents, various dramatic side effects may occur. Numerous data demonstrate that dietary components and phytoantioxidants play a significant role in preventing or reducing the damage induced by HMs. This review summarises the role of various phytochemicals, plant and herbal extracts or probiotics in promoting human health by mitigating the toxic effects of different HMs.

Indexed as

chelation therapyheavy metalshuman healthphytoantioxidantsplant and herbal extractsprobiotics

Identifiers

PMID38611284
PMCPMC11012104
OpenAlexW4393067908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.