Evidence map›Paper›PMID 38611072›Full record

ArticleCancers2024

Dermoscopy as a Tool for Identifying Potentially Metastatic Thin Melanoma: A Clinical-Dermoscopic and Histopathological Case-Control Study.

Vincenzo De Giorgi, Flavia Silvestri, Giovanni Cecchi, Federico Venturi, Biancamaria Zuccaro, Gabriella Perillo, Federica Cosso, Vincenza Maio, Sara Simi, Pietro Antonini and 4 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Vincenzo De GiorgiSection of Dermatology, Department of Health Sciences, University of Florence, 50121 Florence, Italy.ORCID 0000-0001-6531-7998
Flavia SilvestriSection of Dermatology, Department of Health Sciences, University of Florence, 50121 Florence, Italy.ORCID 0000-0003-1629-1458
Giovanni CecchiSection of Dermatology, Department of Health Sciences, University of Florence, 50121 Florence, Italy.
Federico VenturiSection of Dermatology, Department of Health Sciences, University of Florence, 50121 Florence, Italy.ORCID 0000-0001-5053-4172
Biancamaria ZuccaroSection of Dermatology, Department of Health Sciences, University of Florence, 50121 Florence, Italy.ORCID 0000-0003-1060-3211
Gabriella PerilloSection of Dermatology, Department of Health Sciences, University of Florence, 50121 Florence, Italy.
Federica CossoMedical Oncology Unit, Careggi University Hospital, 50134 Florence, Italy.
Vincenza MaioSection of Pathology, Department of Health Sciences, University of Florence, 50121 Florence, Italy.
Sara SimiSection of Pathology, Department of Health Sciences, University of Florence, 50121 Florence, Italy.ORCID 0000-0001-6145-8275
Pietro AntoniniSection of Pathology, Department of Health Sciences, University of Florence, 50121 Florence, Italy.
Serena PillozziMedical Oncology Unit, Careggi University Hospital, 50134 Florence, Italy.ORCID 0000-0001-8861-8718
Lorenzo AntonuzzoMedical Oncology Unit, Careggi University Hospital, 50134 Florence, Italy.
Daniela MassiSection of Pathology, Department of Health Sciences, University of Florence, 50121 Florence, Italy.ORCID 0000-0002-5688-5923
Laura DoniMedical Oncology Unit, Careggi University Hospital, 50134 Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite being early-stage tumors, thin cutaneous melanomas contribute significantly to mortality and have a rising incidence. A retrospective case-control study was performed to identify clinical-dermoscopic and histopathological variables linked to local and distant metastases in melanomas ≤0.8 mm. Data from 1 January 2000 to 22 June 2022 were analyzed from two Italian skin cancer referral centers. Sixteen patients with ≤0.8 mm melanomas developing metastases were studied compared to controls without metastases over 5 years. Statistical analysis involved Pearson's chi-squared test or Fisher's exact test. Of the 1396 cases, 1.1% progressed. The median diagnosis age was 49 (range 28-83), with 56.3% men and 43.7% women. The torso was the primary tumor site (43.7%). Clinically, lesions were pigmented (>10 mm diameter: 73.3%, ≥3 colors: 80%). Dermoscopically, the common features were white patches (73.3%), atypical vascular patterns (66.5%), blue-gray areas (60%) and absent pigment networks (60%). Histopathologically, all cases had adverse features like regression (87.4%), dermal mitoses (50%), a vertical growth phase (62.5%) and ulceration (12.5%). These findings were statistically significant compared to controls (

Indexed as

dermatoscopydermoscopyearly-stage melanomametastasisskin cancertumor thickness

Identifiers

PMID38611072
PMCPMC11010964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.