Evidence map›Paper›PMID 38611039›Full record

ReviewCancers2024

Zebrafish-A Suitable Model for Rapid Translation of Effective Therapies for Pediatric Cancers.

Debasish Roy, Bavani Subramaniam, Wai Chin Chong, Miriam Bornhorst, Roger J Packer, Javad Nazarian

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Debasish RoyCenter for Genetic Medicine Research, Children's National Hospital, Washington, DC 20012, USA.ORCID 0000-0003-4233-3295
Bavani SubramaniamCenter for Genetic Medicine Research, Children's National Hospital, Washington, DC 20012, USA.
Wai Chin ChongCenter for Genetic Medicine Research, Children's National Hospital, Washington, DC 20012, USA.
Miriam BornhorstCenter for Genetic Medicine Research, Children's National Hospital, Washington, DC 20012, USA.ORCID 0000-0002-7595-7726
Roger J PackerCenter for Genetic Medicine Research, Children's National Hospital, Washington, DC 20012, USA.
Javad NazarianCenter for Genetic Medicine Research, Children's National Hospital, Washington, DC 20012, USA.ORCID 0000-0002-1951-9828
Children's National · US

Funding

Anonymous family donor PID 30007084
6 · The paper itself

Abstract

Pediatric cancers are the leading cause of disease-related deaths in children and adolescents. Most of these tumors are difficult to treat and have poor overall survival. Concerns have also been raised about drug toxicity and long-term detrimental side effects of therapies. In this review, we discuss the advantages and unique attributes of zebrafish as pediatric cancer models and their importance in targeted drug discovery and toxicity assays. We have also placed a special focus on zebrafish models of pediatric brain cancers-the most common and difficult solid tumor to treat.

Indexed as

animal modelbrain tumorsdrug toxicitypediatric cancerstargeted therapyzebrafish

Identifiers

PMID38611039
PMCPMC11010887
OpenAlexW4393356950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.