Evidence map›Paper›PMID 38610984›Full record

ArticleCancers2024

Prognostic Importance of Axillary Lymph Node Response to Neoadjuvant Systemic Therapy on Axillary Surgery in Breast Cancer-A Single Center Experience.

Cvetka Grašič Kuhar, James Geiger, Fabienne Dominique Schwab, Viola Heinzelmann-Schwartz, Marcus Vetter, Walter Paul Weber, Christian Kurzeder

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Cvetka Grašič KuharDepartment of Medical Oncology, Institute of Oncology, 1000 Ljubljana, Slovenia.ORCID 0000-0001-5047-4034
James GeigerBreast Cancer Center, University Hospital Basel, University of Basel, 4001 Basel, Switzerland.ORCID 0000-0003-2441-2504
Fabienne Dominique SchwabBreast Cancer Center, University Hospital Basel, University of Basel, 4001 Basel, Switzerland.ORCID 0000-0003-1124-3780
Viola Heinzelmann-SchwartzDepartment of Gynecologic Oncology, University Hospital Basel, 4031 Basel, Switzerland.
Marcus VetterMedical Faculty, University of Basel, 4001 Basel, Switzerland.ORCID 0009-0004-1003-1078
Walter Paul WeberBreast Cancer Center, University Hospital Basel, University of Basel, 4001 Basel, Switzerland.
Christian KurzederBreast Cancer Center, University Hospital Basel, University of Basel, 4001 Basel, Switzerland.
University of Basel · CHUniversity Hospital of Basel · CHUniversity of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neoadjuvant systemic treatment (NST) is the standard treatment for HER2+, triple-negative (TN), and highly proliferative luminal HER2- early breast cancer. Pathologic complete response (pCR) after NST is associated with improved outcomes. We evaluated the predictive factors for axillary-pCR (AXpCR) and its impact on the extent of axillary node surgery. This retrospective study included 92 patients (median age of 50.4 years) with an initially node-positive disease. Patients were treated with molecular subtype-specific NST (4.3% were luminal A-like, 28.3% luminal HER2-, 26.1% luminal HER2+, 18.5% HER2+ non-luminal, and 22.8% TN). Axillary-, breast- and total-pCR were achieved in 52.2%, 48.9%, and 38% of patients, respectively. In a binary logistic regression model for the whole population, the only independent factor significantly associated with AXpCR was breast-pCR (OR 7.4; 95% CI 2.6-20.9;

Indexed as

axillary surgerybreast cancerneoadjuvant systemic therapynodal responsepathologic complete response

Identifiers

PMID38610984
PMCPMC11010874
OpenAlexW4393218907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.