Evidence map›Paper›PMID 38610947›Full record

ArticleCancers2024

Sperm-Associated Antigen 5 Knockout Reduces Doxorubicin and Docetaxel Resistance in Triple-Negative Breast Cancer MDA-MB-231 and BT549 Cells.

Ji He, Jiawei Li, Yanbiao Liu, Yan Li

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Ji HeSchool of Science, Auckland University of Technology, Auckland 1010, New Zealand.ORCID 0000-0003-4181-9760
Jiawei LiSchool of Science, Auckland University of Technology, Auckland 1010, New Zealand.
Yanbiao LiuSchool of Science, Auckland University of Technology, Auckland 1010, New Zealand.
Yan LiSchool of Science, Auckland University of Technology, Auckland 1010, New Zealand.ORCID 0000-0002-2781-2119
Auckland University of Technology · NZ

Funding

Faculty of Health and Environmental Science (Auckland University of Technology, NZ) Research and Development Fund 2022
6 · The paper itself

Abstract

Sperm-associated antigen 5 (SPAG5), also known as Astrin, was previously demonstrated as a biomarker for cellular resistance to major breast cancer therapies, including chemo-, endocrine- and targeted therapy. However, the contribution of SPAG5 to anthracycline- and taxane-based chemotherapy in triple-negative breast cancer (TNBC) remains controversial. In the present study, the

Indexed as

AstrinCRISPR-Cas9docetaxeldoxorubicinknockoutSPAG5triple-negative breast cancer

Identifiers

PMID38610947
PMCPMC11010853
OpenAlexW4393159391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.