Evidence map›Paper›PMID 38610922›Full record

ArticleCancers2024

Immunotherapy and Cannabis: A Harmful Drug Interaction or Reefer Madness?

Brian J Piper, Maria Tian, Pragosh Saini, Ahmad Higazy, Jason Graham, Christian J Carbe, Michael Bordonaro

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Brian J PiperDepartment of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA 18509, USA.ORCID 0000-0002-2295-445X
Maria TianDepartment of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA 18509, USA.
Pragosh SainiDepartment of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA 18509, USA.
Ahmad HigazyDepartment of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA 18509, USA.
Jason GrahamDepartment of Mathematics, University of Scranton, Scranton, PA 18510, USA.
Christian J CarbeDepartment of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA 18509, USA.
Michael BordonaroDepartment of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, PA 18509, USA.ORCID 0000-0002-6667-0096
Geisinger Commonwealth School of Medicine · USCenter for Innovation · USUniversity of Scranton · US

Funding

MODE OF ACTION OF ENVIRONMENTAL TOXICANTST32ES007060 · NIEHS · OREGON STATE UNIVERSITY · PI Jamie DeWitt, Siva Kumar Kolluri · 1985 to 2026
$11.6M
NIEHS NIH HHS T32 ES007060-31A1
6 · The paper itself

Abstract

A retrospective (N = 140) and a prospective (N = 102) observational Israeli study by Bar-Sela and colleagues about cannabis potentially adversely impacting the response to immunotherapy have together been cited 202 times, including by clinical practice guidelines. There have also been concerns on PubPeer outlining irregularities and unverifiable information in their statistics and numerous errors in calculating percentages. This reanalysis attempted to verify the data analysis while including non-parametric statistics. The corrected prospective report contained 22

Indexed as

ipilimumabmarijuananivolumabpembrolizumab

Identifiers

PMID38610922
PMCPMC11011043
OpenAlexW4393094160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.