Evidence map›Paper›PMID 38610173›Full record

ArticleHealthcare (Basel, Switzerland)2024

Minimally Invasive Treatment of Stress Urinary Incontinence in Women: A Prospective Comparative Analysis between Bulking Agent and Single-Incision Sling.

Lorenzo Campanella, Gianluca Gabrielli, Erika Chiodo, Vitaliana Stefanachi, Ermelinda Pennacchini, Debora Grilli, Giovanni Grossi, Pietro Cignini, Andrea Morciano, Marzio Angelo Zullo and 6 more

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Lorenzo CampanellaDepartment of Obstetrics and Gynaecology, Ospedale Sandro Pertini, 00157 Rome, Italy.
Gianluca GabrielliDepartment of Obstetrics and Gynaecology, Ospedale Sandro Pertini, 00157 Rome, Italy.
Erika ChiodoDepartment of Obstetrics and Gynaecology, Ospedale Sandro Pertini, 00157 Rome, Italy.
Vitaliana StefanachiDepartment of Obstetrics and Gynaecology, Ospedale Sandro Pertini, 00157 Rome, Italy.
Ermelinda PennacchiniDepartment of Obstetrics and Gynaecology, Ospedale Sandro Pertini, 00157 Rome, Italy.
Debora GrilliDepartment of Obstetrics and Gynaecology, Ospedale Sandro Pertini, 00157 Rome, Italy.
Giovanni GrossiDepartment of Obstetrics and Gynaecology, Ospedale Sandro Pertini, 00157 Rome, Italy.
Pietro CigniniDepartment of Obstetrics and Gynaecology, Ospedale Sandro Pertini, 00157 Rome, Italy.
Andrea MorcianoDepartment of Obstetrics and Gynaecology, Pia Fondazione Cardinale G. Panico, 73039 Tricase, Italy.ORCID 0000-0001-5420-4277
Marzio Angelo ZulloAIUG Research Groups, Associazione Italiana di UroGinecologia e del Pavimento Pelvico, 00168 Rome, Italy.
Pierluigi PalazzettiDepartment of Obstetrics and Gynaecology, Ospedale Sandro Pertini, 00157 Rome, Italy.
Carlo RappaAIUG Research Groups, Associazione Italiana di UroGinecologia e del Pavimento Pelvico, 00168 Rome, Italy.ORCID 0009-0009-3346-7153
Marco CalcagnoDepartment of Obstetrics and Gynecology, Santo Spirito Hospital, 00193 Rome, Italy.
Vincenzo SpinaMaternal and Child Department, S. Camillo de Lellis Hospital, 02100 Rieti, Italy.
Mauro CervigniAIUG Research Groups, Associazione Italiana di UroGinecologia e del Pavimento Pelvico, 00168 Rome, Italy.
Michele Carlo SchiaviDepartment of Obstetrics and Gynaecology, Ospedale Sandro Pertini, 00157 Rome, Italy.
University of Rome Tor Vergata · ITAssociazione Italiana Di Oncologia Medica · ITOspedale Sandro Pertini · ITFerioli & Gianotti (Italy) · ITOspedale di Santo Spirito · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe study aims to compare the efficacy and safety of bulking agents and single-incision slings in the treatment of urinary incontinence in 159 patients during a 29-month follow-up period. MATERIAL AND

methodsOf the 159 patients suffering from stress urinary incontinence, 64 were treated with bulking agents (PAHG Bulkamid

resultsThe bulking agents showed high efficacy and safety during the 29-month follow-up. Post-operative complications were recorded in both groups, with only two significant differences. The Bulkamid group experienced no pain, while 10.8% of the ALTIS group experienced groin pain and 5% experienced de novo urgency. Furthermore, patients treated with bulking agents experienced reduced nicturia (0.78 vs. 0.92 in patients treated with single-incision slings.). In both groups, we noticed a significant improvement in QoL (quality of life), with a halved ICIQ-UI-SF (International Consultation on Incontinence Questionnaire-Urine Incontinence-Short Form) score which was completed to assess the impact of urine symptoms. After 24 months of therapy, the Bulkamid group saw a decrease from 14.58 ± 5.11 at baseline to 5.67 ± 1.90 (

conclusionsIn terms of efficacy and safety, bulking agents had notable results over the 29-month follow-up period. Furthermore, the patients treated with bulking agents reported a lower incidence of postoperative complications and a no discernible difference in terms of quality of life and sexual activity compared to the ones treated with single-incision slings. Bulking agents can be considered a very reliable therapeutic option based on accurate patient selection.

Indexed as

Intrinsic Sphincteric Deficiencymidurethral slingsingle-incision slingstress urinary incontinenceurethral bulking agents

Identifiers

PMID38610173
PMCPMC11012214
OpenAlexW4393352990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.