ArticleNature chemistry2024
Mechanically triggered on-demand degradation of polymers synthesized by radical polymerizations.
Article in Nature chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Precise Structural Design for Chemically Recyclable Polymers.Precision chemistry · 2026Review
- Boosting Natural Rubber Performance by Backbone Rigid Functionalization.Angewandte Chemie (International ed. in English) · 2026Article
- Force Reveals Hidden Conformations and Dissociation Pathways in Individual π-Interacting Dimers.Angewandte Chemie (International ed. in English) · 2026Article
- Photoreforming and Photoelectroreforming of Waste-Derived Feedstocks for Solar-Driven Production of Fuels and Chemicals.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Development and application of a poly (sodium p-styrenesulfonate-co-acrylic acid) / Ficus leaves-derived activated carbon composite for the efficient removal of 4-nitrophenol from aqueous solutions.Scientific reports · 2026Article
- Mechanically Triggered Chemical Recyclable Polyethylene-Like Materials.Angewandte Chemie (International ed. in English) · 2026Article
- Soft, Flexible, and Stretchable Platforms for Tissue-Interfaced Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Mechanomedicine.Nature reviews bioengineering · 2026Article
- Conformational preorganization of neighbouring groups modulates and expedites polymer self-deconstruction.Nature chemistry · 2026Article
- Dynamic decrosslinking enables self-healing, reprocessability, and upcycling in polyurethane networks.Nature communications · 2026Article
- Cycloreversion-enhanced toughness and degradability in mechanophore-embedded end-linked polymer networks.Nature communications · 2026Article
- Mapping structures and dynamics with frequency-correlated diffusion exchange.Science advances · 2025Article
- Orthogonal and Multiresponsive Quinolinone Systems for Reversible and Recyclable Polymer Networks.Journal of the American Chemical Society · 2025Article
- Logic-Gated Release of a Dual Payload from a β-Lactam Mechanophore with a Rotaxane Actuator.Angewandte Chemie (International ed. in English) · 2025Article
- Smart and Biodegradable Polymers in Tissue Engineering and Interventional Devices: A Brief Review.Polymers · 2025Review
- On-demand, readily degradable Poly-2,3-dihydrofuran enabled by anion-binding catalytic copolymerization.Nature communications · 2025Article
- Diverse reactivity of maleimides in polymer science and beyond.Polymer international · 2025Article
- Harnessing Non-Thermal External Stimuli for Polymer Recycling.Macromolecules · 2025Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polymers that degrade on demand have the potential to facilitate chemical recycling, reduce environmental pollution and are useful in implant immolation, drug delivery or as adhesives that debond on demand. However, polymers made by radical polymerization, which feature all carbon-bond backbones and constitute the most important class of polymers, have proven difficult to render degradable. Here we report cyclobutene-based monomers that can be co-polymerized with conventional monomers and impart the resulting polymers with mechanically triggered degradability. The cyclobutene residues act as mechanophores and can undergo a mechanically triggered ring-opening reaction, which causes a rearrangement that renders the polymer chains cleavable by hydrolysis under basic conditions. These cyclobutene-based monomers are broadly applicable in free radical and controlled radical polymerizations, introduce functional groups into the backbone of polymers and allow the mechanically gated degradation of high-molecular-weight materials or cross-linked polymer networks into low-molecular-weight species.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.