Evidence map›Paper›PMID 38609673›Full record

ArticleJournal of pharmacokinetics and pharmacodynamics2024

Five multivariate Duchenne muscular dystrophy progression models bridging six-minute walk distance and MRI relaxometry of leg muscles.

Deok Yong Yoon, Michael J Daniels, Rebecca J Willcocks, William T Triplett, Juan Francisco Morales, Glenn A Walter, William D Rooney, Krista Vandenborne, Sarah Kim, DMD MR Biomarker Steering Committee

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmacokinetics and pharmacodynamics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01484678 (Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01484678 recruitingnot on this map

Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy

TypeobservationalSponsorUniversity of FloridaRan2020 to 2026Enrolled550ConditionsDuchenne Muscular Dystrophy, Becker Muscular Dystrophy
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Deok Yong YoonDepartment of Pharmaceutics, Center for Pharmacometrics and Systems Pharmacology, College of Pharmacy, University of Florida, Orlando, FL, USA.
Michael J DanielsDepartment of Statistics, University of Florida, Gainesville, FL, USA.
Rebecca J WillcocksDepartment of Physical Therapy, University of Florida, Gainesville, FL, USA.
William T TriplettDepartment of Physical Therapy, University of Florida, Gainesville, FL, USA.
Juan Francisco MoralesDepartment of Pharmaceutics, Center for Pharmacometrics and Systems Pharmacology, College of Pharmacy, University of Florida, Orlando, FL, USA.
Glenn A WalterDepartment of Physiology and Aging, University of Florida, Gainesville, FL, USA.
William D RooneyAdvanced Imaging Research Center, Oregon Health & Science University, Portland, OR, USA.
Krista VandenborneDepartment of Physical Therapy, University of Florida, Gainesville, FL, USA.
Sarah KimDepartment of Pharmaceutics, Center for Pharmacometrics and Systems Pharmacology, College of Pharmacy, University of Florida, Orlando, FL, USA. sarahkim@cop.ufl.edu.ORCID http://orcid.org/0000-0002-9179-0735
DMD MR Biomarker Steering Committee
University of Florida · USOregon Health & Science University · US

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Magnetic Resonance Imaging and Biomarkers for Muscular DystropyR01AR056973 · NIAMS · UNIVERSITY OF FLORIDA · PI VANDENBORNE, KRISTA H · 2010 to 2024
$20.2M
A Prisma Upgrade for the OHSU Advanced Imaging Research Center 3T MRI InstrumentS10OD021701 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI ROONEY, WILLIAM D · 2016 to 2016
$1.6M
Optimizing Muscular Dystrophy Clinical Trial Designs using Modeling and SimulationR21TR004006 · NCATS · UNIVERSITY OF FLORIDA · PI KIM, SARAH · 2021 to 2022
$414k
A High-Performance Computing System for Advanced ImagingS10OD018224 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI ROONEY, WILLIAM D · 2014 to 2014
$222k
NCATS NIH HHS R21 TR004006NCATS NIH HHS UL1 TR001427NCATS NIH HHS UL1 TR002369NIAMS NIH HHS R01 AR056973NIH HHS R01AR056973NIH HHS R21TR004006NIH HHS S10 OD018224NIH HHS S10 OD021701
6 · The paper itself

Abstract

The study aimed to provide quantitative information on the utilization of MRI transverse relaxation time constant (MRI-T

Indexed as

Disease ProgressionLegMagnetic Resonance ImagingMuscle, SkeletalMuscular Dystrophy, DuchenneAdolescentChildHumansLongitudinal StudiesMaleModels, BiologicalProspective StudiesWalkingWalk TestClinical trial simulationDisease progressionDrug development toolsDuchenne muscular dystrophyMagnetic resonance imagingModel-informed drug developmentQuantitative imaging biomarkersRare diseasesSix-minute walk distance

Identifiers

PMID38609673
PMCPMC11470134
OpenAlexW4394769347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.