Evidence map›Paper›PMID 38609582›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2024

Clinical outcomes of triclosan-coated barbed suture in open hernia repair: a retrospective cohort study.

F Berrevoet, L van Cauteren, N Gunja, W A Danker, N-D Schmitz, J Tomaszewski, L Stern, A Chandak

Open access · hybridAbstract read
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Comment to: Clinical outcomes of triclosan-coated barbed suture in open hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

F BerrevoetUniversity Hospital Gent, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
L van CauterenUniversity Hospital Gent, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
N GunjaEthicon Inc., 1000 US-202, Raritan, NJ, 08869, USA.
W A DankerEthicon Inc., 1000 US-202, Raritan, NJ, 08869, USA.
N-D SchmitzEthicon Inc., 1000 US-202, Raritan, NJ, 08869, USA.
J TomaszewskiEthicon Inc., 1000 US-202, Raritan, NJ, 08869, USA.
L SternCertara, 100 Overlook Center, Suite 101, Princeton, NJ, 08540, USA.
A ChandakCertara, 100 Overlook Center, Suite 101, Princeton, NJ, 08540, USA. aastha.chandak@certara.com.
Ghent University Hospital · BECertara (United States) · USIntegra LifeSciences (United States) · US

Funding

Ethicon 1472047
6 · The paper itself

Abstract

purposeWe assessed clinical outcomes of patients undergoing open hernia repair using STRATAFIX™ Symmetric, a barbed triclosan-coated suture (TCS; Ethicon), versus conventional polydioxanone suture (PDS) for abdominal wall closure.

methodsThis single-center retrospective cohort study identified patients undergoing hernia repair. The site used PDS from 2013 to 2016 and switched exclusively to barbed TCS in 2017. Outcomes were assessed at 30, 60, and 90 days. Multivariate regression analyses and Cox proportional hazards models were used.

resultsOf 821 hernia repairs, 446 used barbed TCS and 375 used conventional PDS. Surgical site infections (SSIs) were significantly less frequent with barbed TCS (60 days, 5.9% vs. 11.4%; P = 0.0083; 90 days, 5.9% vs. 11.7%; P = 0.006) and this remained consistent after multivariate adjustment (60 days, OR [95% CI]: 0.5 [0.3-0.9]; 90 days, 0.5 [0.3-0.9]). Among patients with SSI, deep SSIs were less frequent with barbed TCS (60 days, 9.1% vs. 35.7%; P = 0.022; 90 days, 9.1% vs. 34.9%; P = 0.0252). Barbed TCS significantly reduced the risk of perioperative complications (HR [95% CI]: 0.5[0.3-0.8]; P = 0.0058). Hospital length of stay was 2.5 days shorter with barbed TCS (mean [95% CI]: 5.7[4.9-6.6] vs. 8.2[7.3-9.1] days; P < 0.0001). No differences in reoperation rate over time were observed by type of suture (HR[95% CI]:1.3 [0.5-3.4]; P = 0.4793).

conclusionsThis study showed that patients who underwent open hernia repair appeared to recover equally well regardless of the suture type. In addition, the use of barbed TCS was associated with significantly reduced risk of perioperative complications and hospital length of stay.

Indexed as

HerniorrhaphySurgical Wound InfectionSuturesTriclosanAgedAnti-Infective Agents, LocalFemaleHumansLength of StayMaleMiddle AgedPolydioxanoneRetrospective StudiesSuture TechniquesTreatment OutcomeAnti-Infective Agents, LocalPolydioxanoneTriclosanHernioplastyResource utilizationStratafixSurgical site infectionsTriclosan-coated suture

Identifiers

PMID38609582
PMCPMC11297053
OpenAlexW4394769736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.