Evidence map›Paper›PMID 38609156›Full record

ArticleRNA (New York, N.Y.)2024

Cytosolic RNA binding of the mitochondrial TCA cycle enzyme malate dehydrogenase.

Michelle Noble, Aindrila Chatterjee, Thileepan Sekaran, Thomas Schwarzl, Matthias W Hentze

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michelle Noble *European Molecular Biology Laboratory (EMBL), Heidelberg 69117, Germany.ORCID 0000-0002-1603-5887
Aindrila ChatterjeeEuropean Molecular Biology Laboratory (EMBL), Heidelberg 69117, Germany.ORCID 0000-0001-9571-2016
Thileepan SekaranEuropean Molecular Biology Laboratory (EMBL), Heidelberg 69117, Germany.ORCID 0000-0001-8227-3691
Thomas SchwarzlEuropean Molecular Biology Laboratory (EMBL), Heidelberg 69117, Germany.ORCID 0000-0001-7697-7000
Matthias W HentzeEuropean Molecular Biology Laboratory (EMBL), Heidelberg 69117, Germany hentze@embl.org.ORCID 0000-0002-4023-7876
European Molecular Biology Laboratory · DEEuropean Molecular Biology Organization · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several enzymes of intermediary metabolism have been identified to bind RNA in cells, with potential consequences for the bound RNAs and/or the enzyme. In this study, we investigate the RNA-binding activity of the mitochondrial enzyme malate dehydrogenase 2 (MDH2), which functions in the tricarboxylic acid (TCA) cycle and the malate-aspartate shuttle. We confirmed

Indexed as

Citric Acid CycleCytosolMalate DehydrogenaseMitochondriaProtein BindingHEK293 CellsHumansNADRNARNA-Binding ProteinsRNA, MitochondrialMalate DehydrogenaseMDH2 protein, humanNADRNARNA-Binding ProteinsRNA, MitochondrialMDH2metabolic enzymesRNA-binding proteins

Identifiers

PMID38609156
PMCPMC11182015
OpenAlexW4394747681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.