ArticleJournal of neurosurgery. Pediatrics2024
Ventricular catheter tissue obstruction and shunt malfunction in 9 hydrocephalus etiologies.
Article in Journal of neurosurgery. Pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 5 citations in OpenAlex.
- Catheter architecture as a determinant of cerebrospinal fluid flow in pediatric hydrocephalus.Fluids and barriers of the CNS · 2026Article
- Role of cerebroventricular size and surgical placement in modulating catheter flow distribution.Fluids and barriers of the CNS · 2026Article
- When to shunt and when to aspirate? Long-term outcomes from a large stereotactic cohort of cystic craniopharyngiomas.Brain & spine · 2026Article
- Uncloggable ventriculoperitoneal shunt system for hydrocephalus via an integrated soft robotic device: CLEARS device.Biomedical microdevices · 2025Article
- Evaluation of risk factors for obstruction of the intraventricular catheter after ventriculoperitoneal shunting in dogs with congenital internal hydrocephalus.Frontiers in veterinary science · 2025Article
- Quantitative and qualitative investigation of shunt failure in anFrontiers in bioengineering and biotechnology · 2025Article
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Authors and funding
13 authors at 7 institutions in 1 country.
Funding
Abstract
objectiveHydrocephalus is a neurological disorder with an incidence of 80-125 per 100,000 births in the United States. The most common treatment, ventricular shunting, has a failure rate of up to 85% within 10 years of placement. The authors aimed to analyze the association between ventricular catheter (VC) tissue obstructions and shunt malfunction for each hydrocephalus etiology.
methodsPatient information was collected from 5 hospitals and entered into a REDCap (Research Electronic Data Capture) database by hydrocephalus etiology. The hardware samples were fixed, and each VC tip drainage hole was classified by tissue obstruction after macroscopic analysis. Shunt malfunction data, including shunt revision rate, time to failure, and age at surgery, were correlated with the degree of tissue obstruction in VCs for each etiology.
resultsPosthemorrhagic hydrocephalus was the most common etiology (48.9% of total cases). Proximal catheter obstruction was the most frequent cause of hardware removal (90.4%). Myelomeningocele (44% ± 29%), other congenital etiologies (48% ± 40%), hydrocephalus with brain tumors (45% ± 35%), and posthemorrhagic hydrocephalus (41% ± 35%) showed tissue aggregates in more than 40% of the VC holes. A total of 76.8% of samples removed because of symptoms of obstruction showed cellular or tissue aggregates. No conclusive etiological associations were detected when correlating the percentage of holes with tissue for each VC and age at surgery, shunt revision rates, or time between shunt implantation and removal.
conclusionsThe proximal VC obstruction was accompanied by tissue aggregates in 76.8% of cases. However, the presence of tissue in the VC did not seem to be associated with hydrocephalus etiology.
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