Evidence map›Paper›PMID 38608258›Full record

ReviewBlood advances2024

The 2022 review of the 2019 American Society of Hematology guidelines on immune thrombocytopenia.

Cindy E Neunert, Donald M Arnold, Rachael F Grace, Thomas Kuhne, Keith R McCrae, Deirdra R Terrell

Abstract readReview
In one paragraph

Review in Blood advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Correlation between the CD8Frontiers in pediatrics · 2026
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Cindy E NeunertDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0001-6753-6107
Donald M ArnoldDepartment of Medicine, Michael G. DeGroote Centre for Transfusion Research, McMaster University, Hamilton, ON, Canada.ORCID 0000-0003-0943-8853
Rachael F GraceDepartment of Pediatrics, Dana-Farber/Boston Children's Medical Center and Blood Disorders Center, Harvard Medical School, Boston, MA.ORCID 0000-0001-7302-0449
Thomas KuhneDivision of Oncology/Hematology, Pediatric Oncology/Hematology, University Children's Hospital Basel, Basel, Switzerland.ORCID 0000-0002-7387-7028
Keith R McCraeTaussig Cancer Institute and Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Cleveland, OH.ORCID 0000-0001-7340-475X
Deirdra R TerrellDepartment of Biostatistics and Epidemiology, Hudson College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK.ORCID 0000-0003-0794-5851

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractThe 2019 American Society of Hematology (ASH) guidelines for immune thrombocytopenia (ITP) included recommendations on the management of adults (recommendations 1-9) and children (recommendations 10-21) with primary ITP . We describe here the results of a review of the 2019 guidelines by a working group of experts requested by ASH to inform decision-making about the need for and timing of a guideline revision. An updated Medline and Embase search applied the same search terms as in the 2019 ASH guidelines, limited to systematic reviews and clinical trials, from May 2017 to July 2022. There were 193 studies identified, 102 underwent abstract reviews, and 54 full reviews. Each study was assessed based on relevance to the previous recommendation with regard to the population, prioritized outcomes, new outcomes, and study design. Reviewers assessed if the data would change the strength or the directionality of the existing recommendation or merit development of a new recommendation. Based on this review, the ASH Committee on Quality endorsed a focused update on second-line management for adults with ITP. In addition, there will be continued annual monitoring and reviewing of the 2019 ASH guidelines on ITP in full to evaluate when there is sufficient new evidence to warrant additional revisions.

Indexed as

HematologyPractice Guidelines as TopicPurpura, Thrombocytopenic, IdiopathicAdultDisease ManagementHumansSocieties, MedicalUnited States

Identifiers

PMID38608258
PMCPMC11319830

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.